ID A0A2U4CDR9_TURTR Unreviewed; 282 AA.
AC A0A2U4CDR9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1 {ECO:0000313|RefSeq:XP_019803574.1};
GN Name=ALKBH3 {ECO:0000313|RefSeq:XP_019803574.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019803574.1};
RN [1] {ECO:0000313|RefSeq:XP_019803574.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019803574.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
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DR RefSeq; XP_019803574.1; XM_019948015.2.
DR AlphaFoldDB; A0A2U4CDR9; -.
DR GeneID; 101330095; -.
DR InParanoid; A0A2U4CDR9; -.
DR OrthoDB; 36492at2759; -.
DR Proteomes; UP000245320; Chromosome 8.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:InterPro.
DR GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IEA:InterPro.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032854; ALKBH3.
DR PANTHER; PTHR31212; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR PANTHER; PTHR31212:SF4; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000313|RefSeq:XP_019803574.1};
KW Oxidoreductase {ECO:0000313|RefSeq:XP_019803574.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 90..220
FT /note="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"
FT /evidence="ECO:0000259|Pfam:PF13532"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 282 AA; 32241 MW; 7330251E48076A2A CRC64;
MEDKRRRARV QGAWAGPAKS QAIAQPAPTA ENHLQQRPGQ TWMNKEHRLS DRQFVFKEPQ
EVVRRAPEPQ VIDKEGVYEI SLSPTGVSRV CLYPGFVDLK EADSVFEQLC QDVPWKQRTG
IREDVTYQQP RLTAWYGELP YTYSRITLEP NPHWHPVLLM LKNQIEENTG HTFNSLLCNL
YRNEKDSVDW HSDDEPSLGR CPIIASLSFG ATRMFEMRKK PPPHLDHTSK KNQCNECCFL
GREWGLHICG QSEVTLGSRN LVTHGRSHPS RLAASSAQGV PF
//
