ID A0A2U4CRD2_TURTR Unreviewed; 869 AA.
AC A0A2U4CRD2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Host cell factor 2 isoform X2 {ECO:0000313|RefSeq:XP_019808014.1};
GN Name=HCFC2 {ECO:0000313|RefSeq:XP_019808014.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019808014.1};
RN [1] {ECO:0000313|RefSeq:XP_019808014.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019808014.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_019808014.1; XM_019952455.2.
DR AlphaFoldDB; A0A2U4CRD2; -.
DR GeneID; 101335745; -.
DR OrthoDB; 5477547at2759; -.
DR Proteomes; UP000245320; Chromosome 11.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00063; FN3; 2.
DR Gene3D; 6.10.250.2590; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR043536; HCF1/2.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR46003; HOST CELL FACTOR; 1.
DR PANTHER; PTHR46003:SF2; HOST CELL FACTOR 2; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF13854; Kelch_5; 2.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 664..756
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 485..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 869 AA; 95536 MW; D1E2C34E8D240AE7 CRC64;
MAAPSLLNWR RVSSFTGPVP RARHGHRAVA IRELMIIFGG GNEGIADELH VYNTVTNQWF
LPAVRGDIPP GCAAHGFVCD GTRILVFGGM VEYGRYSNEL YELQASRWLW KKVKPYPPSS
GLPPCPRLGH SFSLYGNKCY LFGGLANESE DSNNNVPRYL NDFYELELQH GSGVVGWSIP
VTKGIVPSPR ESHTAVIYCR RDSGSPKMYV FGGMCGARLD DLWQLDLETM SWSKPETKGT
VPLPRSLHTA SVIGNKMYIF GGWVPHKGEN IETSPHDCEW RCTSSFSYLN LDTAEWTTLV
SDSQEDKKNS RPRPRAGHCA VAIGTRLYFW SGRDGYKKAL NSQVCCKDLW YLDTDASDIL
SNFLILKKFL LLQSEMIAFH KLSTPIILES PFIIFLGISF ASHLCWIPCF LDLIFFPSLV
YILIFVEHIP GKGCIEKPPA PSQVQLIKAT TNSFHVKWDE VPTVEGYLLQ LNTDLPYQAV
SSDSSATPNM QGVRMDPHRQ GSNSIIPNSI SDTMNSAKSE HTAMKGTSLK NKPELKASTD
SNATLHSSLA TNASNHNSCV VDMLRKNEGP HTSVNIGVLS SCLDLRTVIP ETSVSSTVSN
AQTMVTQQTI KTESSSTNGA VVKDETSLTT FSTKSEVDET CALPATKISR VEAHAAVMPF
SKETPSNPVA TMKAGERQWC DVGIFKNNTA LVSQFYLLPK GKQSISKIGN ADVPDYSLLK
KQDLVPGTGY RFRVAAINGC GIGPFSKISE FKTCIPGFPG APSAVRISKN VEGIHLSWEP
PTSPSGNILE YSAYLAIRTA QIQDNPSQLV FMRIYCGLKT SCIVTAGQLA NAHIDYTSRP
AIVFRISAKN EKGYGPATQV RWLQVTIIA
//
