ID A0A2U4CRL4_TURTR Unreviewed; 2441 AA.
AC A0A2U4CRL4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Nucleoprotein TPR {ECO:0000256|ARBA:ARBA00019789};
GN Name=TPR {ECO:0000313|RefSeq:XP_019808086.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019808086.1};
RN [1] {ECO:0000313|RefSeq:XP_019808086.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019808086.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TPR family. {ECO:0000256|ARBA:ARBA00005274}.
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DR RefSeq; XP_019808086.1; XM_019952527.2.
DR GeneID; 101332337; -.
DR OrthoDB; 3135837at2759; -.
DR Proteomes; UP000245320; Chromosome 1.
DR GO; GO:0034399; C:nuclear periphery; IEA:UniProt.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 2.
DR InterPro; IPR012929; TPR/MLP1.
DR PANTHER; PTHR18898:SF2; NUCLEOPROTEIN TPR; 1.
DR PANTHER; PTHR18898; NUCLEOPROTEIN TPR-RELATED; 1.
DR Pfam; PF07926; TPR_MLP1_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 1115..1242
FT /note="Nucleoprotein TPR/MLP1"
FT /evidence="ECO:0000259|Pfam:PF07926"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 711..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 991..1011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1695..1750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1878..2183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2305..2441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 105..241
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 295..357
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 397..442
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 503..589
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 619..679
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 741..877
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1297..1492
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1530..1557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1695..1712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1713..1750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1878..1903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1956..1974
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1981..2013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2020..2060
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2075..2089
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2096..2145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2146..2165
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2305..2338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2374..2403
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2441 AA; 275494 MW; BE0E7D3019837CFB CRC64;
MPSSGPVSKS RQRGRPMASR SCDRSRRLSL RRAGARETPS EVAEAAAQAS GSSSSSSFFS
VSAPSAAAAT VPGPIDMAAV LQQVLERTEL NKLPKSVQNK LEKFLADQQS EIDGLKGRHE
KFKVESEQQY FEIEKRLSHS QERLVNETRE CQSLRLELEK LNSQLKVLTE KNKELEVAQD
RNIAIQSQFT RTKEELEAEK RDLIRTNERL SQELEYLTED VKRLSEKLKE SNATKGELQL
KFDELQASDV SVKYREKRLE QEKELLHNQN TWLNTELKTK TDELLALGRD KGNEILELKC
NLENKKEEVS RMEEQMNGLK TSNENLQKHV EDLLTKLKEA KEQQASMEEK FHNELNAHIK
LSNLYKSAAD DSEAKSNELT RAVDELHKLL KEAGEANKAI QDHLLEVEES KDQMEKEMLE
KIRKLEKELE NANDLLSATK RKGAILSEEE LAAMSPTAAA VAKIVKPGMK LTELYNAYVE
TQDQLLLEKL ENKRINKYLD EIVKEVEAKA PILKRQREEY ERAQKAVASL SVKLEQAMKE
IQRLQEDTDK ANKHSSVLER DNQRMEVQIK DLSQQIRVLL MELEEARGNH VIRDEEVSSA
DISSSSEVIS QHLVSYRNIE ELQQQNQRLL VALRELGETR EREEQETTSS KITELQLKLE
SALAELEQLR ESRRHQMQLV DSIVRQRDMY RILLSQTTGV TIPLQASSLD DSSLVSTQKR
SSTSQTVSTP TPVPVIESAE AIEAKAALKQ LQEIFENYKK EKADNEKMQN EQLEKLQEQV
TDLRSQNTKI STQLDFASKR YEMLQDNVEG YRREITSLHE RNQKLTAATQ KQEQIINTMT
QDLRGANEKL AVAEVRAENL KKEKEMLKLS EVRLSQQRES LLAEQRGQNL LLTNLQTIQG
ILERSETETK QRLSSQIEKL EHEISHLKKK LENEVEQRHT LTRNLDVQLL DTKRQLDTET
NLHLNTKELL KNAQKEIATL KQHLSNVEVQ LASQSSQRTG KGQPSNKEDV DDLLSQLRQA
EEQVNDLKER LKTSTSNVEQ YRAMVTSLEE SLNKEKQVTE EVHKNIEVRL KESAEFQTQL
EKKLMEVEKE KQELQDDKRR AIESMEQQLS ELKKTLNSVQ NEVQEALQRA GTALSNEQQA
RRDCQEQAKI AVEAQNKYER ELMLHAADVE ALQAAKEQVS KMVSVRQHLE ETTQKAESQL
LECKASWEER ERMLKDEVSK SVSRCEDLEK QNRLLHDQIE KLSDKIVASM KEGVQGPLNV
SLSEEGKSQE QILEILRFIR REKEIAETRF EVVQVESLRY RQRVELLERE LQELQDSLNA
EREKVQVTAK TMAQHEELMK KTETMNVVME TNKMLREEKE RLEQDLQQMQ AKVRKLELDI
LPLQEANAEL SEKSGMLQAE KKLLEEDVKR WKARNQHLVS QQKDPDTEEY RKLLSEKEVH
AKRIQQLTEE TGRLKAEIAR SNASLTNNQN LIQSLKEDLN KVRTEKESIQ KDLDAKIIDI
QEKVKTITQV KKIGRRYKTQ YEELKAQQDK VMETSAQSSG EHQEQHVSVQ EMQELKETLN
QAETKSKSLE SQVENLQKTL SEKEMEARSL QEQTVQLQSE LSRLRQDLQD RTTQEEQLRQ
QITEKEEKTR KAIVAAKSKI AHLAGVKDQL TKENEELKQR NGALDQQKDE LDVRMTALKS
QYEGRISRLE RELREHQERH LEQRDEPQEP TNKVPEQQRQ ITLKTAPTSG ERGIASTSDP
PTANIKPTPV VSTPSKVTAA AMAGNKSTPR ASIRPMVTPA TVTNPTTTPT ATVMPTTQVE
SQEAMQSEGP VEHVPVFGST SGSVRSTSPN VQPSIPQPIL TVQQQTQATA FVQPTQQSHP
QIEPTNQELS PNIVEVVQSS PVERPSTSTA VFGTVSATPS SSLPKRTREE EEDSTIEASD
QISDDTVEMP LPKKLKSVTP VGTEEEVMAE ESTDGEVETQ VYNQDSQDSI GEGVTQGDYT
PMEDSEETSQ SLQIDLGPLQ SDQQTTSSQD GQGKGDDVIV IDSDDEEEDD DENDGEHEDY
EEDEEEDDDD EDDTGMGDEG EDSNEGTGSA DGNDGYEADD AEGGDGTDPG TETEESMGGG
ESNQRAADSQ NSGEGNTGTA ESSFSQEISR EQQPSSASER QTPRAPQSPR RPPHPLPPRL
TIHAPPQELG PPVQRIQMTR RQSVGRGLQL TPGIGGMQHF FDDEDRTVPS TPTLVVPHRT
DGFAEAIHSP QVAGVPRFRF GPPEDMPQTS SSHSDLGQLA SQGELSLGLG MYETPLFLAH
EEESGGRSVP TTPLQVAAPV TVFTESTTSD ASEHASQSVP MVTTSTGTLS TTNETATGDD
GDEVFVEAES EGISSEAGLE IDSQQEEEPV QASDESDLPS TSQDPPSSSS VDTSSSQPKP
FRRVRLQTTL RQGVRGRQFN RQRGMSHAMG GRGGINRGNI N
//
