ID A0A2U8FSA9_9BURK Unreviewed; 380 AA.
AC A0A2U8FSA9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=DEH84_06715 {ECO:0000313|EMBL:AWI53156.1};
OS Aquabacterium olei.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Aquabacterium.
OX NCBI_TaxID=1296669 {ECO:0000313|EMBL:AWI53156.1, ECO:0000313|Proteomes:UP000244892};
RN [1] {ECO:0000313|EMBL:AWI53156.1, ECO:0000313|Proteomes:UP000244892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110486 {ECO:0000313|EMBL:AWI53156.1,
RC ECO:0000313|Proteomes:UP000244892};
RA Tang B., Chang J., Zhang L., Yang H.;
RT "complete genome sequence of Aquabacterium olei NBRC 110486.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; CP029210; AWI53156.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U8FSA9; -.
DR KEGG; aon:DEH84_06715; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000244892; Chromosome.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AWI53156.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000244892}.
FT DOMAIN 16..362
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 380 AA; 41029 MW; 663BE0A04294B7AA CRC64;
MPADSLILTD VVGGLGVITL HRPKALNALT LEMVRELTVV LRGWATDPAV LGVLLRGSAR
PPMEGKPVVT HFCAGGDIRF MHDAALAGDP AIEDFFTEEY ALDHLIHVYP KPTVAWMDGI
TMGGGMGLAQ GCDLRVATAS LRMAMPETRI GLFPDVGGGY FLSRLAGHAG EYLGVVGPHL
HVTDALALGL ADMHAESACL ASLLDGLRAG PARDADELMA RVRGHVAQHP LGALPEATTT
ARFADIDRHF SGHTLQDIVA SLEAARAAGD TWAAETLQHM AGHSPLMMGV TLEQIRRARS
MPLAEVFRME RTMVRHCFQL RKGRDSETVE GVRALVVDKD HAPRWQPAAV AEVQPQMVEA
FFEGVWPPHA HPLRDLHDPL
//
