ID   A0A2U8GVE6_9RHOO        Unreviewed;       260 AA.
AC   A0A2U8GVE6;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=protein acetyllysine N-acetyltransferase {ECO:0000256|ARBA:ARBA00012928};
DE            EC=2.3.1.286 {ECO:0000256|ARBA:ARBA00012928};
GN   ORFNames=CEW83_20065 {ECO:0000313|EMBL:AWI77243.1};
OS   Parazoarcus communis.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC   Parazoarcus.
OX   NCBI_TaxID=41977 {ECO:0000313|EMBL:AWI77243.1, ECO:0000313|Proteomes:UP000244930};
RN   [1] {ECO:0000313|EMBL:AWI77243.1, ECO:0000313|Proteomes:UP000244930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TSPY31 {ECO:0000313|EMBL:AWI77243.1,
RC   ECO:0000313|Proteomes:UP000244930};
RA   Woo J.-H., Kim H.-S.;
RT   "Azoarcus.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP022187; AWI77243.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U8GVE6; -.
DR   KEGG; acom:CEW83_20065; -.
DR   Proteomes; UP000244930; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd01407; SIR2-fam; 1.
DR   Gene3D; 3.30.1600.10; SIR2/SIRT2 'Small Domain; 1.
DR   Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   InterPro; IPR003000; Sirtuin.
DR   InterPro; IPR026591; Sirtuin_cat_small_dom_sf.
DR   InterPro; IPR026590; Ssirtuin_cat_dom.
DR   PANTHER; PTHR11085:SF12; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11085; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF02146; SIR2; 1.
DR   SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR   PROSITE; PS50305; SIRTUIN; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00236};
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244930};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00236}.
FT   DOMAIN          4..260
FT                   /note="Deacetylase sirtuin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50305"
FT   ACT_SITE        131
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT   BINDING         139
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT   BINDING         142
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT   BINDING         160
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
FT   BINDING         163
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00236"
SQ   SEQUENCE   260 AA;  28162 MW;  29DF63FDA0FA9025 CRC64;
     MTVSSSTNAD IDAVAALLKH AERVLFITGA GISADSGLPT YRGIGGLYHE RLTAEGLTIE
     EALSGEMMAQ RPDISWRYIG EIESNCRGAK PSAAHLRIAD LEAEKPGVWV LTQNVDGLHR
     MAGSEKVIQI HGTVHHLRCT ECPHQRSVHD FAGLDLPPAC PVCGGVLRPD IVLFGEMLPQ
     KGLDQLTHVL ESGVDLIVSI GTTSVFPYIS GPVWWAQQNG IPSVEINPGD TEVSDIVDYR
     LRMGAADAMT QLWARMHELP
//