ID A0A2U8UGS5_9CAUD Unreviewed; 608 AA.
AC A0A2U8UGS5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AWN02378.1};
GN Name=46 {ECO:0000313|EMBL:AWN02378.1};
GN ORFNames=SEA_CONCEPTII_46 {ECO:0000313|EMBL:AWN02378.1};
OS Mycobacterium phage ConceptII.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Fromanvirus.
OX NCBI_TaxID=2178920 {ECO:0000313|EMBL:AWN02378.1, ECO:0000313|Proteomes:UP000246835};
RN [1] {ECO:0000313|EMBL:AWN02378.1, ECO:0000313|Proteomes:UP000246835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Colquhoun J.M., Fisher J.M., Kenna M.A., Mageeney C.M., Marzillier J.Y.,
RA Swartz E.W., Timmel A.E., Vecchio A.C., Ware V.C., Bowman C.A.,
RA Russell D.A., Pope W.H., Jacobs-Sera D., Hatfull G.F.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; MH230876; AWN02378.1; -; Genomic_DNA.
DR Proteomes; UP000246835; Genome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00023109};
KW Viral DNA replication {ECO:0000256|ARBA:ARBA00023109}.
FT DOMAIN 15..192
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT DOMAIN 372..555
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
SQ SEQUENCE 608 AA; 67590 MW; 973EA4014E3BB847 CRC64;
MKQHRYQIKD ETVLVNVVEH EDDLDGFESF IRSNLRILGL DTETTDLGIY KPDFGIRLIQ
FGNPWESWVL PVERGGAFVG AAVTALQKVQ RFVIHNAAFD LQVIERTLGV PMEQMWPKVE
DTKIYSHLVD PRAYKEGGTG HKLEELTKFY IDPVTAEEVK ASMARLAKKH KTTKDKIWAL
VDLDDPDYEL YAGMDTILVS RLLGKVAPLV PESSHKLIPY EHKLAEVMSY VERTGFLLDV
DYSEKLSADM LRKSEHYTAV ARYAYGVDSV NSTEKLADGL ERAGVKIKGR TATGKRQVNA
ELLEALAEEG NALAKAAIEA KKWGSWEKTW VRNFIERRDA NDRVHPGINP LQARTARMST
TSPSAQNLPA NDWMVRRCFL ADPGQLMVSV DYQAQELRVL AALANDRTMI RAFEEEADLH
QVTADAAGMD RKVGKMANFL TVYGGGAGKL ATNAGITFPE AKKVLDIFAA TYPGVTDLSK
SLQREAANLG YVITPTGRRL PVDPDRGYAA LNYMVQSTSR DVTASAVLRL HEAGMTPMIR
LVIHDEVLAS VPEAEAEVTA KEIGRIMEQT FRGVLINTDP EVGGRSWGAA YLKKDEQPSA
DPFLRIPA
//
