ID A0A2U9AZ72_SCOMX Unreviewed; 357 AA.
AC A0A2U9AZ72;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative iroquois-class homeodomain protein IRX-2 {ECO:0000313|EMBL:AWO96908.1};
GN ORFNames=SMAX5B_012188 {ECO:0000313|EMBL:AWO96908.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWO96908.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWO96908.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TALE/IRO homeobox family.
CC {ECO:0000256|ARBA:ARBA00008446}.
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DR EMBL; CP026243; AWO96908.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9AZ72; -.
DR Proteomes; UP000246464; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR003893; Iroquois_homeo.
DR PANTHER; PTHR11211; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX; 1.
DR PANTHER; PTHR11211:SF15; IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-2; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00548; IRO; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000313|EMBL:AWO96908.1};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000313|EMBL:AWO96908.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464}.
FT DOMAIN 241..258
FT /note="Iroquois-class homeodomain protein"
FT /evidence="ECO:0000259|SMART:SM00548"
FT REGION 113..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..135
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..196
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..245
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 357 AA; 39055 MW; D62F53D6A1EA84A8 CRC64;
MAGALSYHPY GSPGYPYQLN DPAYRKNATR DATATLKAWL QEHRKNPYPT KGEKIMLAII
TKMTLTQKNL DNGEASADDE GISLHVDTLT DHSCSAESDG EKVNCRVGEL GSERARDKCD
DDDEDEEEDE DAEDEEDRNH RNHRSHRSHR SHDPRAQLSP KVVVTSSPLT GVEAPLLGHH
PHHQQHHLHH QHLQHLHQLH SQREDLARGL ASGGGGGGVV VGAGKPPPCL DSRAPSGPPP
NPAAKPKLWS LAEIATSDQK QQHQQQQPGV INTAVGRIGH YGLPAGPFPG AFSARFRMGQ
PCLLHYGTVD RSPCDTRSTV CFAVNGATLS ELNPALRRAP LKLLGEETRL PLTPPRY
//
