ID A0A2U9B2D9_SCOMX Unreviewed; 828 AA.
AC A0A2U9B2D9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Putative semaphorin-3A {ECO:0000313|EMBL:AWO98104.1};
GN ORFNames=SMAX5B_007777 {ECO:0000313|EMBL:AWO98104.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWO98104.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWO98104.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; CP026244; AWO98104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9B2D9; -.
DR STRING; 52904.ENSSMAP00000002352; -.
DR Proteomes; UP000246464; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd05871; Ig_Sema3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF71; SEMAPHORIN-3AA; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..476
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 554..616
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 687..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..740
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..796
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 828 AA; 92594 MW; AF98143916209600 CRC64;
MLDSSNLVTF NGLANSSSYD TFLLDEERGR LLVGAEDHIF SFDLVNINRD FKQIAWPATP
SKRDECKWAG KDYGKECSNF IRVLQPYNQT HLYICGTGAF HPICAYLEMG KKAEDNIFRL
GSLFENGRGK SPYDPKMLSA SLLIDGELYS GTSADFMGRD FAIFRTLGDH HPIRTEQHDS
RWLNDPRFIN VHLIPESDNP EDDKLFLFFK ENAMDGENTG KATIARIGQL CKNDMGGHRS
LVNKWTTFLK ARLMCSVPGV NGIDTHFDEL QDVFLMSAKD PKNPVIYAVF TTSSNIFKGS
AVCMYNMADI RRVFLGPYAH RDGPNYQWVP FQGRVPYPRP GTCPSKTFGG FDSTKDLPDD
VITFARGHPA MYNPVHPIGG RPIMVRTDVD YQFSQLVVDR VEAEDGQYDV MFIGTDMGTV
LKVVTIPRES WHDLEEVVLE EMTVFREPTA ITAMELSTKQ QQLYLGSSLG VSQMSLHRCE
VYGKACAECC LARDPYCAWD GTECSRYFPT AKRRTRRQDI RNGDPLSQCS DLQHHEDADG
LGGRVEDRSV FGVENSSMFL ECSPKSQRAL IYWQLQKPND DRKHEIKLDD RVLRTDQGLL
IRSLTQSDTG VYHCQAVEHG FIQPLLRLNL QVIPAQKLGD ILPGLPGAGG GVGQSAKHRV
WYRDFLSLLD HPDLNSVEEF CDRVWKKDRK PKKAKTPNGN DRGKPEGTGA ANSGLRPKAL
APNAQRQQAG PPQSRTWLQA GAPTVEGPAR GQNTQKGQTN LGTLSGQAAK NNAKVQSGQR
GQGSMAGSQA AGGTRANSQH AAKWRRIQEN KKGRNRRTHE LQRPPRSV
//
