ID   A0A2U9B2Q2_SCOMX        Unreviewed;       619 AA.
AC   A0A2U9B2Q2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Putative N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D {ECO:0000313|EMBL:AWO98058.1};
GN   ORFNames=SMAX5B_007829 {ECO:0000313|EMBL:AWO98058.1};
OS   Scophthalmus maximus (Turbot) (Psetta maxima).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC   Scophthalmus.
OX   NCBI_TaxID=52904 {ECO:0000313|EMBL:AWO98058.1, ECO:0000313|Proteomes:UP000246464};
RN   [1] {ECO:0000313|EMBL:AWO98058.1, ECO:0000313|Proteomes:UP000246464}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Martinez P.;
RT   "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT   evaluation of genetic and physical mapping variation across individuals.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Early endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004220}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004220}. Golgi apparatus membrane
CC       {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004395}. Nucleus {ECO:0000256|PROSITE-
CC       ProRule:PRU00376}.
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DR   EMBL; CP026244; AWO98058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U9B2Q2; -.
DR   STRING; 52904.ENSSMAP00000000725; -.
DR   Proteomes; UP000246464; Chromosome 2.
DR   GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16909; YEATS_GAS41_like; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   Gene3D; 2.60.40.1970; YEATS domain; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR038704; YEAST_sf.
DR   InterPro; IPR005033; YEATS.
DR   PANTHER; PTHR15032; N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D; 1.
DR   PANTHER; PTHR15032:SF4; N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   Pfam; PF03366; YEATS; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   PROSITE; PS51037; YEATS; 1.
PE   4: Predicted;
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00376}; Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000246464}.
FT   DOMAIN          367..568
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF12706"
FT   REGION          169..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..247
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   619 AA;  70405 MW;  7F7C894458C342A5 CRC64;
     MFKKMTEFGP DSGGRVKGVT IVKPIVFGNV ARYFGKKREE DGHTHQWSVY VKPYRNEDMS
     AYVKKIQFKL HESYGNPLRV VTKPPYEITE TGWGEFEIII KIFFIDPNER PVTLYHLLKL
     FQSDSSAMPK KTVVSEFYDE MIFQDPTAMM QQLLTTSRQL TLGAYKHETE FSEHEQRTKE
     KMETAKKRTS QEIAELKDKL KASRENINHG GGGGGGVPME KPSSSGRAAL EETTGLVEED
     EVLRGAEGGV VDPRPPRKSS SSRSSRKSFR LDYRLEEEVT KSCRDKHGRW INPWSTWRFP
     SHSMLLRFLL FDKNHSNVPT NKEALDSELP VMEPFFVQNP DLSDSGPGLR VTWLGHATVL
     VEIDGLNILT DPIFSQRASP LQFMGPKRYR GPPCTVEQLP RIDAVVISHS HYDHLDVGSV
     ASLNARFGGE LRWFVPLGLM DWLARMDCEN VMELDWWEEN CVPGHDDITF VCTPSQHWSK
     RTALDDNKSL WGSWTVLGPE HRFFFAGDTG YCSSFLEIGR RFGPFDLAAI PIGAYLPRDV
     MQGQHVDPAE AVQIHQDLQA KQSVAIHWGT FALAHEYYME PPVHLRDALE QKGLNPKSFF
     TLHHGESRLI TSQGGDVFE
//