ID A0A2U9B9Z1_SCOMX Unreviewed; 695 AA.
AC A0A2U9B9Z1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Voltage-gated calcium channel beta 4 subunit transcript variant 2 {ECO:0000313|EMBL:AWP00773.1};
GN ORFNames=SMAX5B_013652 {ECO:0000313|EMBL:AWP00773.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP00773.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP00773.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
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DR EMBL; CP026246; AWP00773.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9B9Z1; -.
DR STRING; 52904.ENSSMAP00000020859; -.
DR Proteomes; UP000246464; Chromosome 4.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd12043; SH3_CACNB4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824:SF15; CALCIUM CHANNEL, VOLTAGE-DEPENDENT, BETA 4B SUBUNIT; 1.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 75..144
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 12..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 149..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..645
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 695 AA; 77018 MW; 505A61DEB3A8BEC8 CRC64;
MYDNLYLHGF EDSEAGSADS YTSRPSDSDV SLEEEREVPA QVQSQSPSQS QGPGQSRQER
EQQATIQLER AKTKPVAFAV RTNVSYCGAL DEDVPVPATA ISFDAKDFLH IKEKFNNDWW
IGRLVKEGCE IGFIPSPLKL ENIRLQQEQK RGRVQGKSGG NSSSSVEDEV SASIRPLISS
AGKQKQKVTE HIPPYDVVPS MRPVVLVGPS LKGYEVTDMM QKALFDFLKH RFDGRISITR
VTADISLAKR SVLNNPSKRA IIERSNTRSS LAEVQSEIER IFELARSLQL VVLDADTINH
PAQLLKTSLA PIIVHVKVSS PKVLQRLVKS RGKSQSKHLN VQLVAADKLA QCPPEMFDII
LDENQLEDAC EHLAEYLEAY WKATHTSMAT PLNPLLGRNL GPTTLTPYPT SISGLQPQAS
LVSKRCRPKY RDKLLNVRLP PRNNDIQTSP TRSHPEPCRP DNTKPESPLS FSSHLSPARS
QQSSRPETDS YMEMKTKHCS VAACRMVGWE TGEQEEEEEE EEEEEGLGYM MMSPQGSHSS
SVLPQGDYVT MATQQKHHWP LSSSPSSGLH SSFNSSTSDS YSPVHPSHYQ ISEHSPPHWQ
LTSVHQSEME ASQSLTSISP STGPQQHRRQ PAETGAASSP VRSVGGSYPM TRPVQVDPNC
GTGRSTRLQA EPDRSAVRRC RLSSCLLSCL QTDPD
//
