ID A0A2U9BK24_SCOMX Unreviewed; 334 AA.
AC A0A2U9BK24;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative alpha-2-HS-glycoprotein {ECO:0000313|EMBL:AWP04404.1};
GN ORFNames=SMAX5B_006646 {ECO:0000313|EMBL:AWP04404.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP04404.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP04404.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP026249; AWP04404.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BK24; -.
DR Proteomes; UP000246464; Chromosome 7.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR025760; Cystatin_Fetuin_A.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR001363; Prot_inh_fetuin_CS.
DR PANTHER; PTHR13814:SF6; ALPHA-2-HS-GLYCOPROTEIN; 1.
DR PANTHER; PTHR13814; FETUIN; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
DR PROSITE; PS51529; CYSTATIN_FETUIN_A; 1.
DR PROSITE; PS01255; FETUIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..334
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016075229"
FT DOMAIN 22..130
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
FT REGION 205..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 34969 MW; 67C942F2271BA24B CRC64;
MSLLGFTVVL GLLLGVWAQH NVLRPLCDSP KAEEAALVAQ DYLNGQHTHG YKYALNRIED
IKVQVEPNGQ ETYVLEIDLL ETNCHVLDPT PLANCSVRPK LLTAVEGDCD VVLKRVGGVL
TVTAFKCKTE ESTEDLCVGC STLLPLNDTA ALDFVQASLA IFNNNTVNVT YTILEVGRMS
SQMPAVDANS TVAAAPAVPP AVHVHTDSLS RRHGLKHHKL TSLHDPQQSG LLSAESAESA
EIVPVVPAVV AAAADPAPAA DPAPTAADPA PTAADPAPTA DSTSDSSSSK EVPVIMFKRD
IAAAAAPAVA DSPAALTDPI LLVPVCPGRV RFFS
//
