ID A0A2U9BKQ4_SCOMX Unreviewed; 361 AA.
AC A0A2U9BKQ4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Heparan sulfate 2-O-sulfotransferase 1 {ECO:0000313|EMBL:AWP04350.1};
GN Name=hs2st1a {ECO:0000313|Ensembl:ENSSMAP00000011730.1};
GN ORFNames=SMAX5B_006058 {ECO:0000313|EMBL:AWP04350.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP04350.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP04350.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSMAP00000011730.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010569}.
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DR EMBL; CP026249; AWP04350.1; -; Genomic_DNA.
DR STRING; 52904.ENSSMAP00000011730; -.
DR Ensembl; ENSSMAT00000011879.2; ENSSMAP00000011730.1; ENSSMAG00000007224.2.
DR GeneTree; ENSGT00530000063408; -.
DR OrthoDB; 5401406at2759; -.
DR Proteomes; UP000246464; Chromosome 7.
DR Proteomes; UP000694558; Chromosome 7.
DR Bgee; ENSSMAG00000007224; Expressed in brain and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12129:SF14; HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transferase {ECO:0000313|EMBL:AWP04350.1}.
FT REGION 52..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 24..51
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 361 AA; 42236 MW; DCB967E6190869E0 CRC64;
MGLLRVMMPP KLQLLALLAF AVAMFFLENQ IQKLEESRGK LERAIARHEV REIEQRHTQD
GLRERDSLAS SQSADGEDDV VIIYNRVPKT ASTSFTNIAY DLCGKNHFHV LHINTTKNNP
VMSIQDQVRF VKNVTEWREM KPAFYHGHVS FLDFTKFGVK RKPIYINVIR DPIERLVSYY
YFLRFGDDYR PGLRRRKQGD KKTFDECVSA GGSDCAPEKL WLQIPFFCGH YSECWNVGSQ
WALEQAKYNL VNEYMLVGVT EELEDFVMML EAALPRFFRG ATELYKTGKK SHLRKTSEKK
APTKESIAKL QQSAIWKMEN EFYEFALEQF QFVRAHAVRE KDGELYLLAQ NFFYEKIYPK
N
//
