ID A0A2U9BLM1_SCOMX Unreviewed; 1083 AA.
AC A0A2U9BLM1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Importin subunit alpha {ECO:0000313|EMBL:AWP04861.1};
GN ORFNames=SMAX5B_016233 {ECO:0000313|EMBL:AWP04861.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP04861.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP04861.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394}.
CC -!- SIMILARITY: Belongs to the taxilin family.
CC {ECO:0000256|ARBA:ARBA00009550}.
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DR EMBL; CP026249; AWP04861.1; -; Genomic_DNA.
DR STRING; 52904.ENSSMAP00000033676; -.
DR Proteomes; UP000246464; Chromosome 7.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0019905; F:syntaxin binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR026183; Taxilin_fam.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF8; IMPORTIN SUBUNIT ALPHA-7; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR Pfam; PF09728; Taxilin; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transport {ECO:0000256|PROSITE-ProRule:PRU00561}.
FT DOMAIN 6..69
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 176..204
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 520..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1010..1083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 714..844
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 22..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..537
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..602
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1043
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 121744 MW; 9C5BF7B810761B33 CRC64;
MCFSRPGNEK EPSGSPAKDN YRMNRYKNKA LNPEEMRRRR EEEGIQLRKQ KREQQLFKRR
NVDVLNEEEA MFESPLVDSY LSSPVTEGVI TRDMVEMLFS EDPELQLATT QKFRKLLSKE
PNPPIDEVIN TTGVVERFVE FLKESINCTL QFEAAWALTN IASGTSLQTK TVIEAGAVPI
FIELLNSDFE DVQEQAVWAL GNIAGDSAVC RDYVLNCNIL PPLLMLLTKS TRLTMTRNAV
WALSNLCRGK NPPPAFEKVS PCLPVLSRLL FSSDPDLLAD ACWALSYLSD GPNDKIQAVI
DSGVCRRLVE LLMHTDYKVA SPALRAVGNI VTGDDIQTQV VLNCSALPCL LHLLSSAKES
IRKEACWTIS NITAGNRAQI QTVIDANIFP VLIDILQKAE FRTRKEAAWA ITNATSGGTP
EQIRYLVNLG CIKPLCDLLT VMDSKIVQVA LNGLENILRL GEQEAKQENS GSGVNPYCSL
IEEAYGLDKI EFLQSHDNQE IYQKAFDLIE HYFGVEDEDS SLAPQVDQAN QQFLFPQQEA
PMEGFHKPEM KKQDSDESGA QGGDECQPAV GGTESPAAAR DGSDGASPKE SEPQTPHTDT
PPQGEEAASG VAEAALSRCD MAEELSRQLE DILTTYCRGA RALPNGQSHS PELNGLASGR
EDGKAAGGKV NGGDAGMEKE QKKTQEKKKV KGLGKEITLL MQTLNTLSTP EEKLAGLCRK
YADLLEEHRN TQKQMRVLQK KQSQLVQEKD NLRNEHSKAI LARSKLESLC RELQRHNRTL
KEEGMQRTRL EEEKRKEVTS HFQVTLNDIQ TQMEQHNERN ASLRQENTEL AEKLKKLYEQ
YKLREEHIDK VVKHKDLQQQ LVDAKLHQAQ ELLKESEDRH DREKDFLLKE AVESQRMCEL
MKQQEVHLKQ QLSLYTEKFE EFQTTLSKSN EVFTTFKQEM EKMTKKIKKL EKETAMYRSR
WESSNKALVE MAEEKSVRDR EFEALQGKVQ RLEKLRRALK VERNELNKKV QNLDGQXCGT
AGAPTSDPLT DSPSPPPTDS PLEPNACSVP DSAPCSHSCH CEPKLDTQPR QGEASAQPVT
VQE
//
