ID A0A2U9BLS4_SCOMX Unreviewed; 1068 AA.
AC A0A2U9BLS4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Exportin-1 {ECO:0000313|EMBL:AWP05044.1};
GN ORFNames=SMAX5B_006900 {ECO:0000313|EMBL:AWP05044.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP05044.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP05044.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; CP026250; AWP05044.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BLS4; -.
DR STRING; 52904.ENSSMAP00000034338; -.
DR Proteomes; UP000246464; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF16; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 46..112
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1068 AA; 122638 MW; F299BD26F5A21D27 CRC64;
MPAEMTMLAD HPARQLLDFS QKLDITLLDN VVNSMYHDIG SQQRVAQEVL TNLKDHPDAW
TRVDTILEFS QNMKTKYYAL QILEVVIKTR WKILPRNQCD GIKKYVVGLI IKTSSDPANM
EKEGVYISKL NMILVQILKQ EWPKHWPTFI SDIVGASRTS ESLCQNNMII LKLLSEEVFD
FSSGQMTQVK AKHLKDSMCN EFSQIFQLCQ FVMENSQNAP LVHATLETLL RFLNWIPLGY
VFETKLISTL VYKFLNVPMF RNVTLKCLTE IAGVSVNQYE EQFVNLFTLT MCQLKQMLPL
NTNIRVAYSN GKDDEQNFIQ NLSLFLCTFL KEHEHGQLVE KRLNLRETLM EALHFMLLVS
EVEETEIFKI CLEYWNHLAA ELYRESPFST SSTPLLSDVP PRRHLYLPML SQVRLLMVSR
MAKPEEVLVV ENDQGEVVRE FMKDTDAINL YKNMRETLVY LTHLDYADTE RIMTEKLHSQ
VNGTEWSWRN LNMLCWAIGS ISGAMHEEDE KRFLVTVIKD LLGLCEQKRG KDNKAIIASN
IMYIVGQYPR FLRAHWKFLK TVVNKLFEFM HETHDGVQDM ACDTFIKISQ KCRRHFVQVQ
VGEVMPFIDE ILNNINTIIC DLQPQQVHTF YEAVGYMIGA QTDQAVQELL IEKYMLLPNQ
VWDSIIQQAT KNVDILKDAE TVRQLGSILK TNVRACKAVG HPFVVQLGRI YLDMLNVYKC
LSENISSAVQ TNGEMVTKQP LIRSMRTVKR ETLKLISGWV SRSNDPQMVG ENFVPPLLEA
VLIDYQRNVP AAREPEVLST MATIVNKLGG HITGEIPKIF DAVFECTLNM INKDFEEFPE
HRTHFFYLLQ AATSQCFPAF LSIAPAQFKL ILDSIIWAFK HTMRNVADTG LQILYTLLQN
VSAEEAAAQS FYQTYFCDVL QHIFSVVTDT SHTAGLTMHA TILAYMFNLV EEGKVSVALS
AASPANNQAH VQEYIANLLK TAFPHLQDAQ VKVFVTGLFS LNQDIPAFKE HLRDFLVQIK
EFAGEDTTDL FLEERESSLR QAQEEKHKLQ MSVPGILNPH ELPEEMCD
//
