ID A0A2U9BMG2_SCOMX Unreviewed; 793 AA.
AC A0A2U9BMG2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=phospholipase A2 {ECO:0000256|ARBA:ARBA00013278};
DE EC=3.1.1.4 {ECO:0000256|ARBA:ARBA00013278};
GN ORFNames=SMAX5B_011584 {ECO:0000313|EMBL:AWP05233.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP05233.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP05233.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-
CC glycero-3-phosphocholine + a fatty acid + H(+); Xref=Rhea:RHEA:15801,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28868,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58168; EC=3.1.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00023422};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:15802;
CC Evidence={ECO:0000256|ARBA:ARBA00023422};
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DR EMBL; CP026250; AWP05233.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BMG2; -.
DR STRING; 52904.ENSSMAP00000034679; -.
DR Proteomes; UP000246464; Chromosome 8.
DR GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07212; Pat_PNPLA9; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR047148; PLPL9.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR24139:SF34; 85_88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2; 1.
DR PANTHER; PTHR24139; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13606; Ank_3; 1.
DR Pfam; PF01734; Patatin; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 150..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 218..250
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 315..347
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 348..380
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 469..653
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 793 AA; 87374 MW; 8BB496475EF35DAD CRC64;
MQFLGRLLDT VSSVSTLFTN PYRVRDVPLS DYGGGGKVLL KEEGRILLYR NTNYQSWDGL
LMCPETPTMV LRLFQVASEE DAMNWFAQYA LKLRPFYETL PLKAETTQPI VDCIRQHPDW
SSAHVAVETG LRECLKHNYV QSQINSRDAL GQTPLHRACE RGDLVCVKEL LDESQARTDI
KDHSGETPMH CAAKQDSPAV IQVLCLRLCS GVNELNGNGE TPLHVACRLG RVEGVKALLD
GGAKCDVAGG TGYPIHSAMK YSEKGCVEEI LKADRGQLQA EDSMYGGTPL HWAKTAEMCR
VLLEHGCAVN YLSKTGESAL HILTKRGRFE AAMVLLTHGA NANLKGQDGN TALHLAMKMD
HIDLIKALIV FGADVEIHND LGETPGLIAA RTSKGPNRKI LLDMLCSVGV QRCHPPSPGS
PPPVSYQVKT QGIGFEDIMY VGATIGAMGK GTSEVDGRKM VKTKMDRLLC LDGGGIKGLV
LIQMLIALEK EAGRPTRDLF DWVAGTSTGG ILALAIIHGK SMEYLRCLYF RMKEQVFRGS
RPYESAPLED FLKKEFGENT KMTDVQYPRV MVTSVLADRH PGELHIFRNY NPPSVHRVPP
YATTATYKPI TVPQEQLVWR AARSSGAAPT YFRPMGRFLD GGLLANNPTL DAMSEINQYN
KALKAEGHGE KIKKLGMVVS LGTGKPPQVV VSSVDVFRPS NPLELAKSFV GARELGKMLV
DCCTDSDGCA VDRASAWCEM IDTIYHRLSP QLSQEVMLDE VSDAVLVDML WETQMYLYEK
REMLRSLANV LLG
//
