ID A0A2U9BNU6_SCOMX Unreviewed; 1240 AA.
AC A0A2U9BNU6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative caskin-1-like {ECO:0000313|EMBL:AWP05390.1};
GN ORFNames=SMAX5B_011553 {ECO:0000313|EMBL:AWP05390.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP05390.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP05390.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; CP026250; AWP05390.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BNU6; -.
DR STRING; 52904.ENSSMAP00000004369; -.
DR Proteomes; UP000246464; Chromosome 8.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd09497; SAM_caskin1_2_repeat1; 1.
DR CDD; cd09498; SAM_caskin1_2_repeat2; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR032232; Caskin1-CID.
DR InterPro; IPR035497; Caskin1/2_SAM_1.
DR InterPro; IPR035498; Caskin1/2_SAM_2.
DR InterPro; IPR032117; Caskin_C.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF11; CASKIN-1; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF16907; Caskin-Pro-rich; 1.
DR Pfam; PF16632; Caskin-tail; 1.
DR Pfam; PF16600; Caskin1-CID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 34..66
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 67..99
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 100..132
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 133..157
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 171..203
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 203..235
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 264..330
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 475..538
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 544..608
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 332..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 609..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..787
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 841..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 443..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..719
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..922
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..957
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1072..1091
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1160
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1240 AA; 132557 MW; 775F0B533F6A4FC9 CRC64;
MWMHGDKETG SDGERLKELL GAAKRVNVNI QDADGLSPLH HAALGGNKEL IALLLEAQAA
VDIKDNKGMR PLHYAAWQGK TEPMKMLLKS GSSVNGQSDE GQIPLHLSAQ HGHYDGSEML
LQHQSNPCIS DSAGKTPLDL ACEFGRVGVV QLLLSSNMCA AMIEPKPSDP NGVSPLHLAA
KNGHIEVIRL LIQAGIDINR QAESGTALHQ AALCGKTEVV RLLLDSGISA GVRNTLSQTA
LDIVNQFTTT QASREIKQLL RDASAAMQVR ALKDYCNNYD LTSLNIKAGD IITVLEQHSD
GRWKGCIHDN RTGNDRVGYF PSNMVEVIKR AGSRSADLSP QGSPTLGHQS STSEDIWVLR
KPLAGGERSG SVGSLGSVRS LSSLQSSGNT HVLTTPAPSP HPAPTPGVNT HGLNAPGLHA
QSEGVKLLAT VLSQSVKAKE HLLEQSQSVE QSASSSSCTV HEPRPFERKA EEDDGKKQAV
VAWLGEFQLQ FYTTHFLTAG YDLDTVSRMT PEDLTAIGVM KPGHRKKLTS EISKLPSTDW
LPDHKPANLA EWLSHLGLSQ YYQVLVQNGY ENTDFISDIS LEDLQEIGIT KLGHQKKLML
GVRRLKDLQR GESGPEPPQS PSTPPSSPGG STSSEPRREA RKQRDGAPSP LTKPRPGLTH
SQTPPQTPPQ TPPHARAQQA SPRARPRPST QLAALDSSVP LLRLPSEEEE RRRTHSLIGT
ESDSRYATVC RSSSARTDAL NDVTVNRSHS SVTLRPRRKG RPPTPPKRSC SSITGGDGEG
EEQGEGLLGL PNYRERRASD CGSLGSALRA QDSGLERSEG ASGSVRSLAA MLETSMVGGA
KTLPKNLGSS TNYLQVSPPV LRRQARLGSE EDDALSRRRT ISGPEGIPGD QTDLLPRKPA
QQRPEPRPRS TMVTSASEIT DGTVTLRRKP RPPATDSEAP ASEATAAVTV TTVSDTIRRR
PRVSENAENV LQSNNQPDSP SSHTDSSRKN GGEVQHNGGV VLRQRPVSQA PDRTEPNRES
CEWMEARKSL KPAVSPKPSA VTLRKTQGEP PIPTRRVPIP GPDNAEKAQS PEPKRVPPPV
SPKPRGPPTA PKPGKSTVAS TAMSPSPAAT SPTPAPKPSS PLSAAPLPAP DTPSAPSLSP
GLPLTSPSPA QSPCTPSSHP VKPPRSSIAG LSIDLLGGRE HRLEETSASL AAALQAVEHT
IKEEDAQNDS ISSKKTTVSI LDDIGNMFDD LADQLDAMLD
//
