ID A0A2U9BQU1_SCOMX Unreviewed; 385 AA.
AC A0A2U9BQU1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Putative tumor suppressor candidate 3-like isoform 3 {ECO:0000313|EMBL:AWP05919.1};
GN ORFNames=SMAX5B_007567 {ECO:0000313|EMBL:AWP05919.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP05919.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP05919.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the OST3/OST6 family.
CC {ECO:0000256|ARBA:ARBA00009561}.
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DR EMBL; CP026250; AWP05919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BQU1; -.
DR STRING; 52904.ENSSMAP00000030159; -.
DR OrthoDB; 4604288at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000246464; Chromosome 8.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd02947; TRX_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR021149; OligosaccharylTrfase_OST3/OST6.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12692; DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12692:SF1; TUMOR SUPPRESSOR CANDIDATE 3; 1.
DR Pfam; PF04756; OST3_OST6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 236..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 385 AA; 43816 MW; 3A0F3A1649C6ACAF CRC64;
MFSITAFAAR HKNYKSQRLR RSERLHADWT TQNPIRWQRH VSQSEHPSVM ATVSAKTFAS
LSVLPVFFLL LLCLPPGGGQ KKKENLLSEK VDQMMEWSSR RSVVRMNGDK FRRFVKAPPR
NYSVIVMFTA LQPQRQCSVC RQANEEYQVL ANSWRYSSAF SNKLFFTVVD YDEGADVFQQ
LNMNSAPTFM HFPAKGKPKR ADTFDLQRIG FASEQLAKWI ADRTDVQIRV FRPPNYSGTI
ALALLVSLVG GLLYLRRNNL EFIYNKTGWA MAALCVVFAM TSGQMWNHIR GPPYAHKNPQ
NGQVSYIHGS SQAQFVAESH IILLLNAAIT MGMVLLNEAA TSKGDVGKRR IICLVGLGLV
VFFFSFLLSI FRSKYHGYPY SFLIK
//
