ID A0A2U9BW96_SCOMX Unreviewed; 1195 AA.
AC A0A2U9BW96;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Putative multiple C2 and transmembrane domain-containing protein 2-like {ECO:0000313|EMBL:AWP08504.1};
GN ORFNames=SMAX5B_009790 {ECO:0000313|EMBL:AWP08504.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP08504.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP08504.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP026252; AWP08504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9BW96; -.
DR STRING; 52904.ENSSMAP00000003066; -.
DR Proteomes; UP000246464; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08376; C2B_MCTP_PRT; 1.
DR Gene3D; 2.60.40.150; C2 domain; 3.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR013583; MCTP_C.
DR PANTHER; PTHR45911; C2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45911:SF9; MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00168; C2; 3.
DR Pfam; PF08372; PRT_C; 1.
DR SMART; SM00239; C2; 3.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 3.
DR PROSITE; PS50004; C2; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 970..995
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1071..1092
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 416..534
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 619..731
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 769..886
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 233..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 375..402
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 297..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1195 AA; 135696 MW; A6DD514CFB4DF068 CRC64;
MWLPSSWNNW AGLNALICGI LAVVETHPVR LLGWLSCLLG NLLLLSVETE SVCGSSAEQV
SVKMEVKKKT FFENLRLKTK LPNLKKPGKK ALAKKGKKLA YRRSISVPDL RIVPGEVPST
ESAFVSNGSD NNIFGISPRW SDTDSVASGS VTDGPIFTDK LNISLPEITP RIRRDRRAAA
LNRISAPAQI LALNEKTDDS VNSGSENKVM FTQEPLYAQV NKGSKGRVQN FTFDPVPAPR
SIFTNTQTSS PRPERVERER LSGEDAAAET IFSGRLAAAL ARAQSLGEQA SPQIEKRSSS
FEHRKPPSEN KTPPVIKRAA PPESMFLTLD SLLESADGTS LDSACGTPNE ERVGMPWATD
SEELDREPGS PVLMRDFYTE EALLEEDQRE EAQEEMEEMS SEPCDLFEEN AQYLSENSAI
TGVPDAQERV LFQRYLLNIN LKQGRNLAIR NKRSGTSDPY VKFKLEGKQF YKSKVVYKNL
NPRWNESFSH PLRDREHDVE VRVYDKNRTA DEFMGCGAIS LKNLHLYKTY EMELRLDDPK
SKEDDMGVIV VDVCLMFRDA TIKRSPRWPV KKNKFYREPF FFCNAYYFQR YHEKNIVFSP
CVPTTETGNV FQTGGGRMRP AETPRNPQRN QKWSGVLGIT LVEGQDLPQD GHGDIYVRFR
LCDQKYKSKN LCIQANPQWR EQFDFNQFED NQEPLQVEVY SKRGRKGEES WGMFEVDLST
LSFNERHLYT HVLNPGKGRL VFLATLRQCW GVSISDMEIA PLEKPDEKDT IVERFSLKNS
HKCGGEVGFL QVKVIKANDL PPTDLNGKSN SFCVIELGNS KLQTHTVYKS VNPEWNKAFT
FPIKDIHDVI EFTVFDENGE KNPTFLGKVA IPLLRVQKGQ QMCLFLKKED LGSASKGTIT
LVLEVIYNQV RAGIRTFQPK ETKLMEENLK FSKKVLARNI CRVRKISTAV LYTLQYIKSC
FQWESTQRSL IAFLIFLVTV WHWELFMLPL FLLLLTGWNY FQLSVGKANS NQDLVNMSMG
DEEEEDEKET GKKGLMDKIH MVQEVVLVVQ NVLEEIANIG ERVKNIFNWS VPFLSFMACL
VLFVSTALLY YIPLRYIVLI WGVNKFTKKL RNPYTIDNNE ILDFLKRVPS DVQKVQYSAL
RAPTSQSQPR RKSSNYWLLS LPSVCSRAAP LLHSPQAIEY VTSAMGPGAQ GHCAP
//
