ID A0A2U9C1Z0_SCOMX Unreviewed; 684 AA.
AC A0A2U9C1Z0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN ORFNames=SMAX5B_014504 {ECO:0000313|EMBL:AWP09686.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP09686.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP09686.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; CP026253; AWP09686.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9C1Z0; -.
DR STRING; 52904.ENSSMAP00000004698; -.
DR Proteomes; UP000246464; Chromosome 11.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd04150; Arf1_5_like; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045872; Arf1-5-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR12027:SF76; PROTEIN WNT-10B; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00025; Arf; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SMART; SM00097; WNT1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 684 AA; 76242 MW; 40D0038E3A75450F CRC64;
MELSNKLRWD QFLILAAALM SPAVTVLCND ILGLKVAGDP VLTPNSVCLR LAGLSKRQMR
MCVRSPDVTA SALQGIQVAI HECQHQFRDQ RWNCSSLEGL GKLPNHNTIL NRGFRESAFS
LALLAAGVAH SVATACSMGK LRGCGCEAKR RQDDDKIRLK LTQLQLQTLQ KGGVGIGMTR
SLPLELNGRH GDLPANLRSA HPSALLTPLP DELSAMQETW EWGGCSHDVR FGERFSRDWL
DSSGSPRDIH ARMRIHNNRV GRQTVNDNMK RKCKCHGTSG SCQFKTCWHV SPEFRLVGSL
LKEKFLSAIF VNSQNKNNGV FNPRTGNIAS RSTGGLNGGR RRSMSRELVY FEKSPDFCER
DASVDSPGTQ GRICNKTSYS TDSCSSLCCG RGHNILKQTR SERCNCRFHW CCYVLCEECR
LTEWVNVCNG VDSRMLVDNQ SCTSSRNVEE VDDKTRERLL HEPTLARTRG VAGGGSSRDF
HPVLCCLTPA GSALPAVERP PVIMGNIFGN LLKSLIGKKE MRILMVGLDA AGKTTILYKL
KLGEIVTTIP TIGFNVETVE YKNISFTVWD VGGQDKIRPL WRHYFQNTQG LIFVVDSNDR
ERVNEAREEL MRMLAEDELR DAVLLVFANK QDLPNAMNAA EITDKLGLHS LRHRNWYIQA
TCATSGDGLY EGLDWLANQL KNKK
//
