ID A0A2U9C620_SCOMX Unreviewed; 735 AA.
AC A0A2U9C620;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 03-MAY-2023, entry version 13.
DE SubName: Full=Putative rho guanine nucleotide exchange factor 37 {ECO:0000313|EMBL:AWP11623.1};
GN ORFNames=SMAX5B_009176 {ECO:0000313|EMBL:AWP11623.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP11623.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP11623.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP026255; AWP11623.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9C620; -.
DR STRING; 52904.ENSSMAP00000011356; -.
DR Proteomes; UP000246464; Chromosome 13.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF9; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 84..271
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 658..722
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..51
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 83051 MW; BFCD9E39180B712E CRC64;
MEVPRRLPPS SFTLTLPKPA ASAPASFVPE KDPEEEENLR EEDEAGEETF ISTEEAEPGA
SVVERSNSNL SSRDSFSEES GGPMQLMAIE ELVQSERNYL RLLQLSTVTI RGNLLKLQPP
LLNLNSMFLH VDEVMDASSR LLSLLDQKRV RPGDPLFLQT LCESFLSLSS DIEAAYKEYL
ANYNHITVVE NSYKQREGLW NEIVRVIKAS APEVNATSLT FFLVMPVQRI ARYPLLLQTI
QKHTDPAHPA YALLEHTAHT SIALNCGINE YKRFREVADK YKKTETLTIK DKINRLNSHS
IAKKTARLSQ QIKHETGITP KLVDEEFDAL QDFFYVLEHG ILELLENVET YLHHLQGFLA
CRTEEFDLDM DGEKAPICYK EITTALRQWI LPTFEKRMRT LIHRPLCALR DLLVGPRNLI
RKRLDKLLDY ELIEAKSNLS YEEHAVANTY RTINTLLLNE LPQFNGVALQ MIWSMLGTFS
CLHRDLASDM EQLFQSFAQQ LPHSSLSPGA FWEWAESMAL EGARRLETLC RSVEDTLNAP
VVQPLSPSSQ RRLKQLMDKH GSGKIWQAAA VVSSRDLDLN LAKGELVAVI SEMDTRGDRR
RWLVDAGGRR GYAPSSKLIR YHQPAEDPPP SPHLTLPDGV TGIRRHSYSP ESRPLTSQPC
FQVMAAYDFA ARGSHEVSLR AGERVRVLEP HDKRGNPEWS LVEARGGQRG YVPSNYLTLM
PLGVGVGPPG SYLPH
//
