ID A0A2U9C6R8_SCOMX Unreviewed; 328 AA.
AC A0A2U9C6R8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Magnesium transporter protein 1 {ECO:0000256|ARBA:ARBA00020885};
DE AltName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1 {ECO:0000256|ARBA:ARBA00030142};
GN Name=magt1 {ECO:0000313|Ensembl:ENSSMAP00000008940.1};
GN ORFNames=SMAX5B_000881 {ECO:0000313|EMBL:AWP12244.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP12244.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP12244.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSMAP00000008940.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the OST3/OST6 family.
CC {ECO:0000256|ARBA:ARBA00009561}.
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DR EMBL; CP026255; AWP12244.1; -; Genomic_DNA.
DR EMBL; CP026255; AWP12245.1; -; Genomic_DNA.
DR STRING; 52904.ENSSMAP00000008928; -.
DR Ensembl; ENSSMAT00000009051.2; ENSSMAP00000008940.1; ENSSMAG00000005520.2.
DR GeneTree; ENSGT00390000012030; -.
DR OMA; IFQQMNL; -.
DR OrthoDB; 4604288at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000246464; Chromosome 13.
DR Proteomes; UP000694558; Chromosome 13.
DR Bgee; ENSSMAG00000005520; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd02947; TRX_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR021149; OligosaccharylTrfase_OST3/OST6.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12692; DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12692:SF2; MAGNESIUM TRANSPORTER PROTEIN 1; 1.
DR Pfam; PF04756; OST3_OST6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..328
FT /note="Magnesium transporter protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040585418"
FT TRANSMEM 179..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 328 AA; 37379 MW; B04F200A625CACF3 CRC64;
MFGKLLISFF LLFVFNHELV DGQKKKETLL SEKVSQMMEW TSKRSVIRLN GDKFRRFVKA
PPRNYSVVIM FTALQPQRQC GVCRQADEEF QVLANSWRYS SAFTNKIFFA SVDFDEGSDV
FQMLNMNSAP TFLHFPSKGK ARKSDTYELQ VRGFAAEQLA RWVADRTDIQ IRVIRPPNYA
GPLLLGFLLA VIGGLAYLRR HNLEFLFNKN VWAFSALCFV LIMTSGQMWN HIRGPPYAHK
NPSTGQVSYI HGSSQAQFVA ETHIVLLFNA AVTMGIVLLC EAATSDIDIG KRKIMCVAGI
GLVMLFFSWL LSIFRAKYHG YPYSFLMT
//
