ID   A0A2U9C8G0_SCOMX        Unreviewed;      1877 AA.
AC   A0A2U9C8G0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Putative lactase-phlorizin hydrolase {ECO:0000313|EMBL:AWP12814.1};
GN   ORFNames=SMAX5B_018535 {ECO:0000313|EMBL:AWP12814.1};
OS   Scophthalmus maximus (Turbot) (Psetta maxima).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC   Scophthalmus.
OX   NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP12814.1, ECO:0000313|Proteomes:UP000246464};
RN   [1] {ECO:0000313|EMBL:AWP12814.1, ECO:0000313|Proteomes:UP000246464}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Martinez P.;
RT   "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT   evaluation of genetic and physical mapping variation across individuals.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP026256; AWP12814.1; -; Genomic_DNA.
DR   STRING; 52904.ENSSMAP00000006516; -.
DR   Proteomes; UP000246464; Chromosome 14.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 4.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR   PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 4.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 4.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 2.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 2.
PE   4: Predicted;
KW   Glycosidase {ECO:0000256|RuleBase:RU004468};
KW   Hydrolase {ECO:0000256|RuleBase:RU004468, ECO:0000313|EMBL:AWP12814.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000246464}.
FT   ACT_SITE        1227
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
FT   ACT_SITE        1698
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   1877 AA;  213603 MW;  AB05D22ADD45F7B8 CRC64;
     MCQRHEDPDQ AMFLAGPITN GQMEGLKGEA SDGALLDTFD CSHPIPPGSR QYFEYLQSRG
     MTHFKMPLSW AQLLPTGRPS QPQQAVVTCY RSLLRQLLEV GLQPLVVLHG STVPQALRSR
     YGGWESQELV DMFQQYAEFV FGEFGELGDP WVTLSSLDEL KGAELRNALD AHSRVYRRYH
     QLFPGRDGQV SVGVRGSKIP IICDSQQLKY LDFLSIKVQY DCTTGQNLAE ELKNVMGKCG
     NKPILLYEVN INDSSPYHFL SDNKIIEVLS NADQSVLGFD MVDLLRPADS IPKRDDTHNK
     KDLQTSSCSI TYCKTWSNFA TMTSSERDAF LNESFPVDFQ WAASSESFKV EGGWSEGGKG
     ETIWDRFGHK GLAFANQTAD LACDSFHKVD YDVYLLRGLH VNTYQFSISW ARIFPSGHRG
     SQSEKGILYY DKLINALIES GIQPVVTLYH WDLPQALQDH GGWTNTSIVE AFKDYADFCF
     SRFGDRVKTW NTFSSPWVVS HVGYGTGEHP PGIMDYVVAS YQATHNILKS HAEAWHVYND
     KYRRKLGGKV GIALNSDWAE PMDPSCPEDI AAADRYLQFM LGWFAHPIFV DGDYPATLKT
     QIEEKRRECP DSEPARLPVF TPQERKRIHG TADFLGLNHY TSRLVNSSNG GCTPGPQGVG
     DFQTHVDPSW SSTASDWIYS TPWGLRRLLN YISTEYLNVT KVPIYITGNG MPTEYSGDTL
     NDTDRIEYMR SYINEALKAI HLDGVDVQRF TVQSLMDGFE GPQGYSERFG LHHINFDLPD
     RPRTPKQSAY FYSEVIEKNG FASKKHFFHS TELKNMKSNR VSSMSPSTVP SQAKDVWRKF
     SNQTNFQRKL YHYGTFPQGF SWGVSSSAYQ IEGGWNADGK GPSIWDTFTH ITGNIPGNPN
     GDVACDSYHR LDEDLYMLRA LRVKSYRFSL SWPRIFPDGQ RTSLNQKGVD YYNRLIDGLL
     AYNITPMVTL YHWDLPQALQ NISGWDNVDM IDIFNDFCDF CFATFGNRVK FWMTFNQPHT
     IAWSGYGLGQ FPPNVKNPGI APYRVAHNLI KAHAKAYHTY DDKYRKSQGG QVSIALNADW
     IEPKDITVPR EVVAADRALQ FQLGWFAHPI FKNGDYPDAM KWHVGNKSEL QGLSESRLPS
     FTEEEKSFIR GTADMFCVNH YTTRIANHAT LRLKPQSYEY DRDLSEAEEG DSPTTAINGQ
     RAVAWGLRRL LNWIREEYGE PDIYITENGV ATDTKTTVDD TDRVFYHKTY IDEALKAHNL
     DGVKVKGYIA TSLMDSFEWL NGYKVGFGLY YVDFTNPNRP KTPKRSAHYY YQIVKDNGFP
     LPADEQVLYG EFPKTFSWST ASASYQIEGS WRAHGKGLSI WDKFAHTPLR VSNSDNGDIA
     CDSYNKIDND VEVLKKLKVS HYRFSISWPR VLPDGTNNYI NEAGLSYYLR LLDALEAANI
     QPQVTLYHWD LPLTLQKVGG WENETIVHRF RDYANVLFSR LGSRVKFWIT LNEPYIVANL
     GYGYGTFAPG IVGKQYIAAH NLIKAHAEAW HLYNDKYRAT QGGIISITIN SDWVEPRNRY
     KQEDVDAAKR YLQFFIGWFA HPIFNGDYPD LMKTIIHRRS LAAGLPKSRL PEFTPAEIKR
     IKGTHDYFGF NHYCSVLSYP VDLGNQQDYE GDRGTGTTHD RTWIESGSFW LKVTPFGFRK
     ILKFIKEEYG NPPIYVTENG ISERGPVDLN DIHRTHYYEN YINQALKAHV LDGVDLRGYT
     AWSLMDNFEW AAGYSERFGL FYVNRSNPTL PRIPKKSASR YSSIITCNGF PDPATGPHDC
     LNPQPEATNA PTVTTPKNTH TTVPVLHLNM VDFLGLELSP HDAEVALYVL FAFLLSTFAV
     TQSFQFRAYF LKHQNNL
//