ID A0A2U9C925_SCOMX Unreviewed; 397 AA.
AC A0A2U9C925;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Putative lupus La protein isoform 3 {ECO:0000313|EMBL:AWP13107.1};
DE SubName: Full=Small RNA binding exonuclease protection factor La {ECO:0000313|Ensembl:ENSSMAP00000022800.2};
GN Name=SSB {ECO:0000313|Ensembl:ENSSMAP00000022800.2};
GN ORFNames=SMAX5B_018436 {ECO:0000313|EMBL:AWP13107.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP13107.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP13107.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSMAP00000022800.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CP026256; AWP13107.1; -; Genomic_DNA.
DR STRING; 52904.ENSSMAP00000022822; -.
DR Ensembl; ENSSMAT00000023062.2; ENSSMAP00000022800.2; ENSSMAG00000013885.2.
DR GeneTree; ENSGT00830000128380; -.
DR OrthoDB; 5477115at2759; -.
DR Proteomes; UP000246464; Chromosome 14.
DR Proteomes; UP000694558; Chromosome 14.
DR Bgee; ENSSMAG00000013885; Expressed in head kidney and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd08028; LARP_3; 1.
DR CDD; cd12291; RRM1_La; 1.
DR CDD; cd12541; RRM2_La; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045180; La_dom_prot.
DR InterPro; IPR006630; La_HTH.
DR InterPro; IPR014886; La_xRRM.
DR InterPro; IPR002344; Lupus_La.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22792:SF172; LUPUS LA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR22792; LUPUS LA PROTEIN-RELATED; 1.
DR Pfam; PF05383; La; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF08777; RRM_3; 1.
DR PRINTS; PR00302; LUPUSLA.
DR SMART; SM00715; LA; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50961; HTH_LA; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS51939; XRRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00332}.
FT DOMAIN 4..96
FT /note="HTH La-type RNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS50961"
FT DOMAIN 108..193
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 226..348
FT /note="XRRM"
FT /evidence="ECO:0000259|PROSITE:PS51939"
FT REGION 199..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 45347 MW; C82E990285D966A5 CRC64;
MAEKQEMSPI EMKVARQVEY YFGDHNLPRD KFLKEQLQVD DGWVTLETML KFNRLKSLTA
ESSVIVAALQ KSKTGLLEIN EDKTKIRRSP DKPLPELNEE YKDTLKNKSV YIKGFPLETT
LDEIQEWLNG KGAIENIQMR RNLQRQFKGS VFICFETEES SKQFLERSDI KSFKDNEMLV
LSREDYHAKK AEERKLFKAE TKAKARQDKE QQQKHAEDKE MGLLLDEQTG CLLKFSGELE
DVSREDFHEL FSGHGKIKWV DFTRGAKEGT LLFDGNAKEA FDKAKEANGG ELKIKKNSVT
WQVIEGDEEK EELKKIIEAQ QESYNRSRGR GGRGRSGGRG GRGGRRGRGG RDHGRNQYQG
KKTKFDSDDE DAPAAPKRER EDADGPAAKV AKTENGS
//
