ID   A0A2U9CN31_SCOMX        Unreviewed;       177 AA.
AC   A0A2U9CN31;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Dickkopf-related protein 3 {ECO:0000313|EMBL:AWP18017.1};
GN   ORFNames=SMAX5B_017387 {ECO:0000313|EMBL:AWP18017.1};
OS   Scophthalmus maximus (Turbot) (Psetta maxima).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC   Scophthalmus.
OX   NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP18017.1, ECO:0000313|Proteomes:UP000246464};
RN   [1] {ECO:0000313|EMBL:AWP18017.1, ECO:0000313|Proteomes:UP000246464}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Martinez P.;
RT   "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT   evaluation of genetic and physical mapping variation across individuals.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the dickkopf family.
CC       {ECO:0000256|ARBA:ARBA00010842}.
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DR   EMBL; CP026260; AWP18017.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U9CN31; -.
DR   STRING; 52904.ENSSMAP00000011500; -.
DR   Proteomes; UP000246464; Chromosome 18.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:InterPro.
DR   Gene3D; 2.10.80.10; Lipase, subunit A; 1.
DR   InterPro; IPR006796; Dickkopf_N.
DR   InterPro; IPR039863; DKK1-4.
DR   PANTHER; PTHR12113:SF31; DICKKOPF-RELATED PROTEIN 3-LIKE; 1.
DR   PANTHER; PTHR12113; DICKKOPF3-LIKE 3; 1.
DR   Pfam; PF04706; Dickkopf_N; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..177
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016063323"
FT   DOMAIN          54..100
FT                   /note="Dickkopf N-terminal cysteine-rich"
FT                   /evidence="ECO:0000259|Pfam:PF04706"
SQ   SEQUENCE   177 AA;  19541 MW;  B938C324C37CA4C1 CRC64;
     MLGNLRMLCL CLCFSWAEAR IWAWMLNMPH SPPKDGAKAL RESAHVSKAT TAVCDHDRNC
     GRGSSCDRHF GLCVPLRGEG HYCRRDAQCV RGLSCMFGKC HRSIPNGQEG ARCKVDRDCG
     ASMCCARHHG EQVCKRRLVG GESCFVPDGG LAFSINQICP CDEGLLCRES SAPHRRE
//