ID A0A2U9CS25_SCOMX Unreviewed; 311 AA.
AC A0A2U9CS25;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Putative tumor necrosis factor receptor superfamily member 16 {ECO:0000313|EMBL:AWP19387.1};
GN ORFNames=SMAX5B_016081 {ECO:0000313|EMBL:AWP19387.1};
OS Scophthalmus maximus (Turbot) (Psetta maxima).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae;
OC Scophthalmus.
OX NCBI_TaxID=52904 {ECO:0000313|EMBL:AWP19387.1, ECO:0000313|Proteomes:UP000246464};
RN [1] {ECO:0000313|EMBL:AWP19387.1, ECO:0000313|Proteomes:UP000246464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Martinez P.;
RT "Integrating genomic resources of turbot (Scophthalmus maximus) in depth
RT evaluation of genetic and physical mapping variation across individuals.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; CP026261; AWP19387.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9CS25; -.
DR STRING; 52904.ENSSMAP00000019900; -.
DR Proteomes; UP000246464; Chromosome 19.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd13416; TNFRSF16; 1.
DR Gene3D; 6.10.250.1780; -; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR041448; TNFR16_TM.
DR InterPro; IPR022325; TNFR_16.
DR InterPro; IPR034046; TNFRSF16_N.
DR PANTHER; PTHR46605; TUMOR NECROSIS FACTOR RECEPTOR; 1.
DR PANTHER; PTHR46605:SF6; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16 ISOFORM X1; 1.
DR Pfam; PF18422; TNFR_16_TM; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR PRINTS; PR01966; TNFACTORR16.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 3.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 4.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:AWP19387.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000246464};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 20..53
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 20..53
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 55..96
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 55..96
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 97..135
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 97..135
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 137..178
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 137..178
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REGION 188..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 33..46
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 75..88
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 78..96
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 114..127
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 117..135
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 138..153
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 311 AA; 33558 MW; AFE3267BBE8DF1E7 CRC64;
MDPEVAFASA SKTERAVLQP CDSGQYTSSG ECCAECPPGE GVVKKCGATQ TVCAQCLDSE
TFSENYSHAE QCKPCTQCTG LMRLQTPCTD SNDAICACNY NYFFNGISGR CEPCTVCPTG
EGVYTHCDHD HDTVCEECVD DTFSDRESSL EPCLPCTICD EETEVQLGVC APTYDSVCHN
PNLPTDITPT SDVPASPPSF TNYFPPDGSE SPLPGAETTT SSAVSPRFLG HGFNENLIPI
YCSILAAVVV GLVAYIVFKR WNSCKQNKQA ANNRAATNNQ MVTPEGEKLH SDSGISVDKQ
RDISVDRDQK Q
//
