ID A0A2U9IIV2_9CREN Unreviewed; 991 AA.
AC A0A2U9IIV2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=FAD-linked oxidase {ECO:0000313|EMBL:AWR95864.1};
GN ORFNames=DFR85_01475 {ECO:0000313|EMBL:AWR95864.1};
OS Acidianus brierleyi.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Acidianus.
OX NCBI_TaxID=41673 {ECO:0000313|EMBL:AWR95864.1, ECO:0000313|Proteomes:UP000248044};
RN [1] {ECO:0000313|EMBL:AWR95864.1, ECO:0000313|Proteomes:UP000248044}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1651 {ECO:0000313|EMBL:AWR95864.1,
RC ECO:0000313|Proteomes:UP000248044};
RA Counts J.A., Kelly R.M.;
RT "Complete Genome Sequences of Extremely Thermoacidophilic, Metal-Mobilizing
RT Type-Strain Members of the Archaeal Family Sulfolobaceae: Acidianus
RT brierleyi DSM-1651T, Acidianus sulfidivorans DSM-18786T, Metallosphaera
RT hakonensis DSM-7519T, and Metallosphaera prunae DSM-10039T.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CP029289; AWR95864.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9IIV2; -.
DR KEGG; abri:DFR85_01475; -.
DR OrthoDB; 26910at2157; -.
DR Proteomes; UP000248044; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006094; Oxid_FAD_bind_N.
DR PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR Pfam; PF01565; FAD_binding_4; 1.
DR Pfam; PF13534; Fer4_17; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248044}.
FT DOMAIN 42..210
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT DOMAIN 506..536
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 991 AA; 110799 MW; 02A9CABABF9D8DD8 CRC64;
MTLRDELESR FRENFSDALV ERLSHSVDMG FVPELVWSGI KINVIPDYVV YPQNTEDIID
LVKIGISNNV PLTPYGRGTN RYGNAIPADG GIVLDFSKMN KIEIDEANRI AVAEAGATWK
LVDIAAQQKG LQLRTFPSSY DSTVGGGTAG DALGVGSYEY GFICDNIAFV EMVNPKGEIV
RLEGKDLAIV CGAEGTTGII TKVGIKLRPF SSTESLVISF EDFEKVYGAI GEFYREVIPA
WHIQVRGPAI SSYIHDKFRA TLDPGKWNMV VLYPSTRSSI VEPKLYKIAQ TYNGKVFEGE
WTGWWSFNHG VNAALRSKGL LIHQHGLLHY TKIKDLIDSI QRDLGNIGVL EPNKGFDLDI
DLERREVLLV NAFTQVSLNP VDRKIIYDLA KNTLMMEDFV KLGGSMLSVG MFVHKYARNR
LSTMGKTFQD LGVDRYEVMK KYKEEMDSEE IFNPGKVFEP KKRAKTVLEI VDKQNEALKF
RFGIGIAKSL SPGGEVEGYK VAKKYLDIFA DYALTCIDCA MCVTVCPQYR LIPQWPYAPK
GMFDFTRGII SYFELHDTVD IPDSTIAEIS GCHKCGLCDG VCPARIPIST LLIKLNSLVA
RKIPEEPTID IRIPDYYKDV ISDDSEIGLW LGRYLSDNPS IVYVTLDLLK RLGLKVKVFG
TSKDSGFMDY ISGNGNSLIE KIKENSNINL LELITISPED YKTFSEAYRE YSKLAGYSNV
FEVVPIEVRL LKSIQFEGND EINLHVACFS SSYADEIIKR LREKGFKVKK IEGCSGAILE
RNLGKRSDRM AKALGETYPN LITLCPLAEM KFRSVGVNAK SLIEFIAEKA GIIISTQVSS
FKVPDEDKKK INDTLLSSIL ASLNKRTQVI ADTLSFISSG PDEYKKIIEP IIVEAMDEVS
QSFVQGIKTM LSNEYGNEDL SKKSIITSTY VKEISSILLS ISLENVIQEL INVIKTITNE
KFDEKTLSSV LLDLIRDNEN KIRSSLVSLS F
//
