ID A0A2U9NVP5_STRAS Unreviewed; 437 AA.
AC A0A2U9NVP5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Leupeptin-inactivating enzyme 1 {ECO:0000313|EMBL:AWT41174.1};
GN ORFNames=DMT42_01750 {ECO:0000313|EMBL:AWT41174.1};
OS Streptomyces actuosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1885 {ECO:0000313|EMBL:AWT41174.1, ECO:0000313|Proteomes:UP000247634};
RN [1] {ECO:0000313|EMBL:AWT41174.1, ECO:0000313|Proteomes:UP000247634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25421 {ECO:0000313|EMBL:AWT41174.1,
RC ECO:0000313|Proteomes:UP000247634};
RA Liu W., Sun F., Hu Y.;
RT "The complete genome sequence of a nosiheptide producer Streptomyces
RT actuosus ATCC 25421: deducing the ability of producing a new class III
RT lantibiotics.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28A subfamily.
CC {ECO:0000256|ARBA:ARBA00005957}.
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DR EMBL; CP029788; AWT41174.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9NVP5; -.
DR KEGG; sact:DMT42_01750; -.
DR OrthoDB; 345880at2; -.
DR Proteomes; UP000247634; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:InterPro.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd03876; M28_SGAP_like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR045175; M28_fam.
DR InterPro; IPR041756; M28_SGAP-like.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR PANTHER; PTHR12147:SF55; PEPTIDE HYDROLASE; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000247634};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..437
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015837087"
FT DOMAIN 317..437
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
SQ SEQUENCE 437 AA; 45721 MW; C2EF4DA0FF950BD1 CRC64;
MNLPARHRAL AVAGLALAGL LAGAVPAATA AEQAAVAAPD IPVANVKQHL ADLQSIANAN
GGNRAHGRSG YRASIDFVKA KLDAAGYTTT LQQFTYNGST GYNLIADRPG GDPDQVIMAG
SHLDSVTAGP GINDNGSGSA AILETALAVA RTGYQPAKHL RFGWWGAEEL GLVGSKYYVN
NLSSTERAKI KGYLNFDMIA SPNPGYFVYD DDPTIEKTFK DYFAGLGIPT EIETEGDGRS
DHAPFKNAGI PVGGLFTGAD YTKTSAQAQK WGGTAGQAFD RCYHSSCDTT ANINDTALDR
NSDAIAHAIW TLTSGTTTPP AGKVFENTTD VAIPDNGAAV TTSVNVTGIT GNAPGNLAVG
VDIVHTWRGD LVVDLVAPDG TVYNLKPFSS SDSADNVQTT YTVDASSETA NGTWKLRVQD
RATYDTGYIN GFKLTFP
//
