ID A0A2U9P8C0_STRAS Unreviewed; 446 AA.
AC A0A2U9P8C0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN ORFNames=DMT42_27940 {ECO:0000313|EMBL:AWT45743.1};
OS Streptomyces actuosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1885 {ECO:0000313|EMBL:AWT45743.1, ECO:0000313|Proteomes:UP000247634};
RN [1] {ECO:0000313|EMBL:AWT45743.1, ECO:0000313|Proteomes:UP000247634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25421 {ECO:0000313|EMBL:AWT45743.1,
RC ECO:0000313|Proteomes:UP000247634};
RA Liu W., Sun F., Hu Y.;
RT "The complete genome sequence of a nosiheptide producer Streptomyces
RT actuosus ATCC 25421: deducing the ability of producing a new class III
RT lantibiotics.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
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DR EMBL; CP029788; AWT45743.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9P8C0; -.
DR KEGG; sact:DMT42_27940; -.
DR OrthoDB; 9814202at2; -.
DR Proteomes; UP000247634; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR NCBIfam; TIGR00836; amt; 1.
DR PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW ECO:0000256|RuleBase:RU362002};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW Reference proteome {ECO:0000313|Proteomes:UP000247634};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362002};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362002};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 138..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 171..195
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 326..345
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 365..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT DOMAIN 20..417
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 446 AA; 46415 MW; EB7EF177AACFEC2A CRC64;
MAPAITLAAE PTLSAANTGF MLICSALVML MTPGLAFFYG GMVRVKSTLN MLMMSFISLG
IVTILWVLYG FSVAFGTDSG SIVGWNSDWV GLSNIGLTEL WDGYTIPVFV FLVFQLMFAI
ITPALISGAL ADRVKFSAWA LFITLWATLV YFPVAHWVWG TGGWAFELGV IDFAGGTAVH
INAGAAALGV ILVIGKRTGF KKDPMRPHSL PLVMLGAGLL WFGWFGFNAG SWLGNDDGVG
ALMFVNTQVA TAAAMLAWLA YEKIRHGAFT TLGAASGAVA GLVAITPAGG AVSPLGAIAV
GVIAGVVCAM AVGLKYRFNY DDSLDVVGVH LVGGVLGSLL IGFFATGKGQ SEVEGLFYGG
GLTQFWKQCA GVFAVLAYSL IVSAILAFLL DKTIGMRVTE DEEVAGIDQA EHAETAYDFS
GAGGGAARTT AVPAPVADTA AKKVDA
//
