ID A0A2U9PCI2_STRAS Unreviewed; 426 AA.
AC A0A2U9PCI2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Inositol phosphorylceramide synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DMT42_01955 {ECO:0000313|EMBL:AWT47397.1};
OS Streptomyces actuosus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1885 {ECO:0000313|EMBL:AWT47397.1, ECO:0000313|Proteomes:UP000247634};
RN [1] {ECO:0000313|EMBL:AWT47397.1, ECO:0000313|Proteomes:UP000247634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25421 {ECO:0000313|EMBL:AWT47397.1,
RC ECO:0000313|Proteomes:UP000247634};
RA Liu W., Sun F., Hu Y.;
RT "The complete genome sequence of a nosiheptide producer Streptomyces
RT actuosus ATCC 25421: deducing the ability of producing a new class III
RT lantibiotics.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP029788; AWT47397.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9PCI2; -.
DR KEGG; sact:DMT42_01955; -.
DR OrthoDB; 4320234at2; -.
DR Proteomes; UP000247634; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03386; PAP2_Aur1_like; 1.
DR InterPro; IPR026841; Aur1/Ipt1.
DR InterPro; IPR045977; DUF5933.
DR PANTHER; PTHR31310; -; 1.
DR PANTHER; PTHR31310:SF7; PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928; 1.
DR Pfam; PF19356; DUF5933; 1.
DR Pfam; PF14378; PAP2_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000247634};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..143
FT /note="DUF5933"
FT /evidence="ECO:0000259|Pfam:PF19356"
FT DOMAIN 160..339
FT /note="Inositolphosphotransferase Aur1/Ipt1"
FT /evidence="ECO:0000259|Pfam:PF14378"
SQ SEQUENCE 426 AA; 46264 MW; 39D2D6EC03526D79 CRC64;
MWIAAGVVAL GFLIALEIAA RHYGVRGPIT NQVREVIFPP KSGPLLYASM ALMMVVLTWR
QRFVAAGVAV GIDIVFALVR WVFDIHTPHG HGFGNGALLV ILGCAVIAVT RRTGQDRVLL
LKGVGLGLLL VAGRKTGDAW LLITSKTRPL VLDPYVATAD HALGDPSWLV GRAVRATGTV
GAHVLDYVYI QLAVAAVVVA LYQLRHVADE RRFPRHHLVR TFLVIGLLGP GIYMLFPTVG
PIFVYGADGG HWAIANLWPE TAPVLQTPHA IPFDEITPRN CMPSLHTAWA TTIFVHSRRG
PRLLRFAGTF WLIATLGATL GFGYHYGVDL IAGVVFALTI EAGLRSLARG WDRAGIQLVA
YGTVVFTALL VSYRFLPMEM ARLPWVFGPL LVLAMVSVIY GYARTTRLWE PVSAPAQPAE
AQPALA
//
