ID A0A2U9R1Y4_PICKU Unreviewed; 741 AA.
AC A0A2U9R1Y4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Pre-mRNA-splicing factor CWC22 {ECO:0000256|ARBA:ARBA00040804};
GN ORFNames=C5L36_0B05180 {ECO:0000313|EMBL:AWU75271.1};
OS Pichia kudriavzevii (Yeast) (Issatchenkia orientalis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=4909 {ECO:0000313|EMBL:AWU75271.1, ECO:0000313|Proteomes:UP000249293};
RN [1] {ECO:0000313|EMBL:AWU75271.1, ECO:0000313|Proteomes:UP000249293}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS573 {ECO:0000313|EMBL:AWU75271.1,
RC ECO:0000313|Proteomes:UP000249293};
RA Douglass A.P., Offei B., Braun-Galleani S., Coughlan A.Y., Martos A.,
RA Ortiz-Merino R.A., Byrne K.P., Wolfe K.H.;
RT "Population genomics shows no distinction between pathogenic Candida krusei
RT and environmental Pichia kudriavzevii: One species, four names.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CWC22 family.
CC {ECO:0000256|ARBA:ARBA00006856}.
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DR EMBL; CP028774; AWU75271.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U9R1Y4; -.
DR STRING; 4909.A0A2U9R1Y4; -.
DR VEuPathDB; FungiDB:C5L36_0B05180; -.
DR OrthoDB; 1115942at2759; -.
DR Proteomes; UP000249293; Chromosome 2.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR PANTHER; PTHR18034:SF3; PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000249293}.
FT DOMAIN 355..473
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 295..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..325
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 86144 MW; 27A9E77253C74924 CRC64;
MSEKLSKLLK LKSGGAYVPP AKLRELMAQV ELEENSKEFQ ILQWEALKKN INSSVNKVNK
KNLKTIVVEL FKNNLLQGRG LLCQCIMKSQ QLSTSYTDVY ASLVSIINSK IPEVGDLLVR
RLIVKFKRLI RRNEAEQCRS VVVFLSELFN FHVINSELVQ QIIDKLFENI SDFRIEMIIE
IMRHCGITLH DENGKWFDQK ANLLRNVLNE NIVNPKSQYL IQEFFDNFKG LVTNYNGIDE
SLDLVEEEDQ ITHNFTLSEN VLGDDHLDVF KFDPNYEDNR EKYNIIRKGI LGSDVETDSD
QEVDNESSDY SSDYDNEEEE KQDVDDDDNR QYTDDKERNK LTVQIKDLTE QELTTFQKNV
YLTIMSSMSP EEATHKLLKL PAVDPKRKEY MLVDMVIKCC AQEKIYSKYY GLIGENLAVI
NKSWAEVFQA LFKENYQNCH RYETALLRNI GAFWGHMFAS DKIGWECLSV IKLTEEDTTS
SGRIFIKFIF QRMVDELGDK KLNERISEDY IQPFIRGLFP VDNPDHLRFS INYFTAIGMG
KLTDKMRSNL NILTEKDKLI TSLVNNGSDS DESDVSSPHR GRSRSRSPHI GRSQSYSRSR
STSRERYNRG TLVSAEDRIG MSSFERERSY SRSRTASPAR QNHKNDRTDN IPKGPRINHN
DNGRGKGHGR GRSGWRGRGR GRGGYSANRS RYRTQENWNY AGRNGSNQFR DDLSYNKRHN
DHQYDHPAAN RDYYNRQREN R
//
