ID A0A2V0PSH7_9CHLO Unreviewed; 633 AA.
AC A0A2V0PSH7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=Rsub_13296 {ECO:0000313|EMBL:GBG00568.1};
OS Raphidocelis subcapitata.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Selenastraceae; Raphidocelis.
OX NCBI_TaxID=307507 {ECO:0000313|EMBL:GBG00568.1, ECO:0000313|Proteomes:UP000247498};
RN [1] {ECO:0000313|EMBL:GBG00568.1, ECO:0000313|Proteomes:UP000247498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-35 {ECO:0000313|EMBL:GBG00568.1,
RC ECO:0000313|Proteomes:UP000247498};
RX PubMed=29795299; DOI=10.1038/s41598-018-26331-6;
RA Suzuki S., Yamaguchi H., Nakajima N., Kawachi M.;
RT "Raphidocelis subcapitata (=Pseudokirchneriella subcapitata) provides an
RT insight into genome evolution and environmental adaptations in the
RT Sphaeropleales.";
RL Sci. Rep. 8:8058-8058(2018).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG00568.1}.
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DR EMBL; BDRX01000249; GBG00568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V0PSH7; -.
DR STRING; 307507.A0A2V0PSH7; -.
DR InParanoid; A0A2V0PSH7; -.
DR Proteomes; UP000247498; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000247498};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 2..157
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 263..601
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 633 AA; 71070 MW; 0B8EB9EE6C1DA7A1 CRC64;
MRRYLLNHQN PDGGFGLHIE GHSTMFGTAL SYVTMRLLGM GPEVPELARA REWIHSRGGA
THITSWGKFW LAVLGVYSWD GMNPLTPEMW LLPYKWWTGV GYLHPGRFWC HCRMVYLPMS
YVYGHRAAAK DSPLTAAIRA ELYPVPYSSI DWNAARNQIA KEDLYYPHPL VQDVLWWALY
KAEALLSGSW LRAAAGREIM RHVHYEDENT RYVDIGPVNK VINMLCCWLE DPNGEALKKH
IPRIYDYLWV AEDGMKMQGY NGSQLWDTSF AVQALIDAGL TDFSSSCLKK AHAYIEQSQV
VQEAEPPLER YYRHISKGAW PFSSRDHGWP ISDCSSEGLK AAVALALLDA RKVGPGIPPE
RLYDAVTVIL SYQNRDGGMA TYENTRSFHS LEIINPAETF GDIIVDYSYV ECTSACITAL
LAFSRQHPQH RPADIARALA RAEAFIRRIQ RPDGSWYGSW GVCFTYAAWF GAAALAALGH
SAHDDPALAR ASAFTVSKQR LDGGWGESYL SCQDKVYSQL EGSASHVVNT AWAMMALMAA
GWHEKDAAPL HRAARYLMSA QLPSGDWPQQ TISGVFNRNC MITYANYRNI FPIWALGLYR
RLVLGGARRL GAEARRPGEA AGWVCAVSDY YTA
//
