ID A0A2V1AQM0_9ASCO Unreviewed; 300 AA.
AC A0A2V1AQM0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Eukaryotic translation initiation factor 2 subunit alpha {ECO:0000313|EMBL:PVH20179.1};
GN ORFNames=CXQ85_001961 {ECO:0000313|EMBL:PVH20179.1};
OS [Candida] haemuloni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45357 {ECO:0000313|EMBL:PVH20179.1, ECO:0000313|Proteomes:UP000244309};
RN [1] {ECO:0000313|EMBL:PVH20179.1, ECO:0000313|Proteomes:UP000244309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B11899 {ECO:0000313|EMBL:PVH20179.1,
RC ECO:0000313|Proteomes:UP000244309};
RA Chow N.A., Gade L., Batra D., Rowe L.A., Ben-Ami R., Loparev V.N.,
RA Litvintseva A.P.;
RT "Genome Sequence of a Multidrug-Resistant Candida haemulonii Isolate from a
RT Patient with Chronic Leg Ulcers in Israel.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eIF-2-alpha family.
CC {ECO:0000256|ARBA:ARBA00007223}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVH20179.1}.
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DR EMBL; PKFO01000003; PVH20179.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1AQM0; -.
DR STRING; 45357.A0A2V1AQM0; -.
DR EnsemblFungi; CXQ85_001961-t46_1; CXQ85_001961-t46_1-p1; CXQ85_001961.
DR VEuPathDB; FungiDB:CXQ85_001961; -.
DR OrthoDB; 4371132at2759; -.
DR Proteomes; UP000244309; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04452; S1_IF2_alpha; 1.
DR Gene3D; 3.30.70.1130; EIF_2_alpha; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR044126; S1_IF2_alpha.
DR InterPro; IPR024055; TIF2_asu_C.
DR InterPro; IPR024054; TIF2_asu_middle_sf.
DR InterPro; IPR011488; TIF_2_asu.
DR PANTHER; PTHR10602; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR PANTHER; PTHR10602:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1; 1.
DR Pfam; PF07541; EIF_2_alpha; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF110993; eIF-2-alpha, C-terminal domain; 1.
DR SUPFAM; SSF116742; eIF2alpha middle domain-like; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:PVH20179.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000244309}.
FT DOMAIN 16..87
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
SQ SEQUENCE 300 AA; 33569 MW; 469B895F3A32AEAA CRC64;
MSTNCRFYEN KYPEVDEVVM VNVQEIAEMG AYVKLLEYDN IEGMVLLSEL SRRRIRSIQK
LIRVGKNEVA VVLRVDKEKG YIDLSKRRVS AEDIVKCDER YNKSKAVHSI LRHCAEKYGV
SLEQLYQTVG WPLSRKYGHA YDAFKLSITD PSIFDGIEAP STEILEELKL YISRRLTPSA
IKIRSDVEVS CFSYEGIDAI KAALEAATSV STEQMQVRAK LIAAPLYEIS TQALDKNQGV
ALLEKAVEKV AEAIEASGGN CKITMAPKAV SASEDAELQA LLERKAAEDK DSSDEEEEED
//
