ID A0A2V1AW80_9ASCO Unreviewed; 1043 AA.
AC A0A2V1AW80;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
GN ORFNames=CXQ85_000555 {ECO:0000313|EMBL:PVH21573.1};
OS [Candida] haemuloni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45357 {ECO:0000313|EMBL:PVH21573.1, ECO:0000313|Proteomes:UP000244309};
RN [1] {ECO:0000313|EMBL:PVH21573.1, ECO:0000313|Proteomes:UP000244309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B11899 {ECO:0000313|EMBL:PVH21573.1,
RC ECO:0000313|Proteomes:UP000244309};
RA Chow N.A., Gade L., Batra D., Rowe L.A., Ben-Ami R., Loparev V.N.,
RA Litvintseva A.P.;
RT "Genome Sequence of a Multidrug-Resistant Candida haemulonii Isolate from a
RT Patient with Chronic Leg Ulcers in Israel.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVH21573.1}.
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DR EMBL; PKFO01000005; PVH21573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1AW80; -.
DR STRING; 45357.A0A2V1AW80; -.
DR EnsemblFungi; CXQ85_000555-t46_1; CXQ85_000555-t46_1-p1; CXQ85_000555.
DR VEuPathDB; FungiDB:CXQ85_000555; -.
DR OrthoDB; 92033at2759; -.
DR Proteomes; UP000244309; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 1.20.970.30; eIF4G, eIF4E-binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022745; eIF4G1_eIF4E-bd.
DR InterPro; IPR036211; eIF4G_eIF4E-bd_sf.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF12152; eIF_4G1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101489; Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000244309}.
FT DOMAIN 671..910
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..145
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..467
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..952
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1043 AA; 113821 MW; C6D1B88723C027E9 CRC64;
MSGKPDTQAD IPPSQKGNAP ASTPSQVAPS AAPAAPGDSQ PHPQNHGSQG FQGGKFPQQS
QQGNYGQNFQ GKPYNRQNQG QAGGQGPQGQ APQGQGQGSA PGTPHQLHQQ PHHQHQQGHR
SGNYQNKNYY NNKRNYNNPK MNNQNQFQNY HYPANMYNYY QMYYQPGMVP GVNMPAGYSP
QSPQLSQSPV QNYPPTASPA GPNKVKITDR EGKQVNLEEK KKSSASSSAS TTPVPSQAQI
VPGAAAPAAK SQTPEASDDQ SASAAAAAAA KKKEAAEEFR RKILEKAKAA KEKKEQEAKA
SAAKSADAAP AAVPAATPAA STSVAAPAAA PTPEESKKAA ETTKEAPVEE SKPEPVKETK
PEPVQETKPE PVEETKPEPV EQAKETPVEE PKEAPVEEKA EPKVEEPVEK APAAEPAAPA
APVVDAPATE VNGDSPETNE TVSETAPTEQ TDDIEEKDEE ATDDDESTEK VFDLSSFFDR
LSTCRAIEDP FTYPYPYPLT GVDARWKAGQ KKYRYDPQFL FQFRDSVAYP IDDAWKEKLE
GLGIVPNRRS GPGGPQRMGS SRFGGQPQGR MGGNMQGRPG QFDGRQNSRS GSRRRGGSNM
GGNPRDRSLR NRNQSRRGPR EKEDDTPAKP AEDVKPLVPS ANRWVPRSRQ KTTEVKTAPD
GTVLLDKEDV ERKVKSALNK LTLEMFEPIS EQMLDIAKQS RHEEDAATIK QVISLTFAKA
CDEPYWSSVY AQFCAKMVKE IPDDIKDVSI LTKSGEPAIG GDLARRILLA TCQSEYEKGW
VDKLPTNPDG SPLEPEMMSD EYYAMAAAKR RGLGLVKFIG NLYILNMLND QVILHCLRDQ
SKNVTDPSED SLENLAQLIK TVGPRFEASE RNKAALNMIF DNVQLILDNC KLSSRIKFML
MDLQDLKKSN WKSLKQESGP KTIKEIHNEA ELKKLEESKA QAEKRRNKGY DRGGYGGGDS
RSNSTRGGAS WGNKKESRAP TKDSRGFQSV PRSQSNRPTP DSSFSASHMS PRENSKRTDS
MASNIFAALD GDNDDNESEG AGH
//
