ID A0A2V1AWL7_9ASCO Unreviewed; 342 AA.
AC A0A2V1AWL7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN ORFNames=CXQ85_005059 {ECO:0000313|EMBL:PVH22490.1};
OS [Candida] haemuloni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45357 {ECO:0000313|EMBL:PVH22490.1, ECO:0000313|Proteomes:UP000244309};
RN [1] {ECO:0000313|EMBL:PVH22490.1, ECO:0000313|Proteomes:UP000244309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B11899 {ECO:0000313|EMBL:PVH22490.1,
RC ECO:0000313|Proteomes:UP000244309};
RA Chow N.A., Gade L., Batra D., Rowe L.A., Ben-Ami R., Loparev V.N.,
RA Litvintseva A.P.;
RT "Genome Sequence of a Multidrug-Resistant Candida haemulonii Isolate from a
RT Patient with Chronic Leg Ulcers in Israel.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVH22490.1}.
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DR EMBL; PKFO01000008; PVH22490.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1AWL7; -.
DR STRING; 45357.A0A2V1AWL7; -.
DR EnsemblFungi; CXQ85_005059-t46_1; CXQ85_005059-t46_1-p1; CXQ85_005059.
DR VEuPathDB; FungiDB:CXQ85_005059; -.
DR OrthoDB; 1200131at2759; -.
DR Proteomes; UP000244309; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05227; AR_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR PANTHER; PTHR10366:SF853; NADPH-DEPENDENT ALDEHYDE REDUCTASE ARI1-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000244309}.
FT DOMAIN 6..259
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT REGION 288..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 37584 MW; B3905E80D20C4A1D CRC64;
MSSTKVLISG ASGFIAVHTV QQLIRNGYTV VGSVRSSEKG EYVKKASGKP DKFSYEIVED
IAKEGAFDEF VKKHSDATVF LHTASPFHYK VTDVETDLLK PAIHGTKNAL SSIAKYGTNI
KRVVVTSSNA AIASRDQDSD PKNVFDETSW NNITWEKALE SPAFGYSGSK AFAERAAWDF
VKEQNPGFVL STVNPVLVFG PQPTNDFNTD KLNTSSEVIN VILKSSSPDD KVAPYNSSAV
DVRDVAKAHL VAFEKDEAKN QRLFLTSDAF TQQTILDVLH EKFPKQTEKV PVGTPGTDKD
EFDQKATKNN DKTRKILGFE LISVRQSIAD SAQQLLQVEG KL
//
