ID A0A2V1B014_9ASCO Unreviewed; 942 AA.
AC A0A2V1B014;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Protein transport protein SEC24 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CXQ85_003742 {ECO:0000313|EMBL:PVH23452.1};
OS [Candida] haemuloni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45357 {ECO:0000313|EMBL:PVH23452.1, ECO:0000313|Proteomes:UP000244309};
RN [1] {ECO:0000313|EMBL:PVH23452.1, ECO:0000313|Proteomes:UP000244309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B11899 {ECO:0000313|EMBL:PVH23452.1,
RC ECO:0000313|Proteomes:UP000244309};
RA Chow N.A., Gade L., Batra D., Rowe L.A., Ben-Ami R., Loparev V.N.,
RA Litvintseva A.P.;
RT "Genome Sequence of a Multidrug-Resistant Candida haemulonii Isolate from a
RT Patient with Chronic Leg Ulcers in Israel.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVH23452.1}.
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DR EMBL; PKFO01000011; PVH23452.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1B014; -.
DR STRING; 45357.A0A2V1B014; -.
DR EnsemblFungi; CXQ85_003742-t46_1; CXQ85_003742-t46_1-p1; CXQ85_003742.
DR VEuPathDB; FungiDB:CXQ85_003742; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000244309; Unassembled WGS sequence.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR PANTHER; PTHR13803:SF39; SECRETORY 24AB, ISOFORM A; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000244309};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 239..276
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 313..552
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 559..641
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 652..754
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 797..857
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 1..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 942 AA; 104824 MW; D3EA7C6DA8817443 CRC64;
MSRRRAYPQP QYAVQQPPAA QPSFNSYGVD QAAQGFQNLN LQQPQQQQQQ QQPQQPSPYP
ANGAGQGYPG QQAPGYGYQA DPYNQPQAQQ PQQAQYPNQY QAPYQNQYQA GYQAPDAYSQ
PSQGSYYGGV GASGATASAA GSLPLNQLYT TDLSKELPPS ISDLTLPPPP LIVPPSSTIV
PGSETANASS EYLRSTLNVI PVNSSLLKKS KLPLALVVRP YTALHESVEN APVTRDTIIS
RCRRCRGYIN PFVSWTEGGK RWRCNFCGLQ NDVPAAFDYD ELSQKSLNRY DRVELNNSCV
EFIAPKEYMA RAPQPIVYTF IIDVSAEAVA TGMTSTVART ILESLDRIPN NNKTARIAIL
GVDSNIHFFR FREGLDEAPE MLIVSDLDEP FLPSPEGLLI NLDENRKALE KMLMEFPNYF
EGTANPHFAL GPALRTGHRL TSNIGGKLVV FSSTLPNIGE GKLAPRDESQ SGKPKESQTL
LVAADKFYKS FAVECNSAQV TIDLFLTGSK YQDVASLSNL PRFTAGQTHF YPSWTCNKEE
DVTKLSKEIS EHLSMEIALE AVLRVRCSTG FRMSGFFGNF FNRSSDLCSF PSFPRDQSYV
IEVSIEETVT KPVVYFQAAV LHTTCYGERR VRVINLAIPT SNKLDDIYAS ADQLAITSYL
THRAIEKALG GSLNDGRDFL FKSVVDILNV YRKDLVPGNV TGSSPLQIST NLRMLPLLLF
ALTKNVGFRD ERLPADHRAI ALNNLGSLPL NHLIKTIYPT VYALHTMPDT CGLPETYIET
DPETGEEHEI TSSDILMPEP QNATKTNWEN YGLYLIDNGN ELFLWVSGDV VPELVADLFG
TQNLYEVVAG KTELPEYSYE ESEFNYKVRQ IIGKLREQRD SIVWKSLYVI IGSGTNEPME
ISQERGLNAL RFWVWSNLVE DKSAHSKGYR DFLTDLKTKI TA
//
