ID A0A2V1B0R3_9ASCO Unreviewed; 519 AA.
AC A0A2V1B0R3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Translation initiation factor eIF2B subunit delta {ECO:0000256|ARBA:ARBA00044147};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit delta {ECO:0000256|ARBA:ARBA00044356};
GN ORFNames=CXQ85_003904 {ECO:0000313|EMBL:PVH23614.1};
OS [Candida] haemuloni.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Metschnikowiaceae incertae sedis;
OC Candida/Metschnikowiaceae.
OX NCBI_TaxID=45357 {ECO:0000313|EMBL:PVH23614.1, ECO:0000313|Proteomes:UP000244309};
RN [1] {ECO:0000313|EMBL:PVH23614.1, ECO:0000313|Proteomes:UP000244309}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B11899 {ECO:0000313|EMBL:PVH23614.1,
RC ECO:0000313|Proteomes:UP000244309};
RA Chow N.A., Gade L., Batra D., Rowe L.A., Ben-Ami R., Loparev V.N.,
RA Litvintseva A.P.;
RT "Genome Sequence of a Multidrug-Resistant Candida haemulonii Isolate from a
RT Patient with Chronic Leg Ulcers in Israel.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PVH23614.1}.
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DR EMBL; PKFO01000011; PVH23614.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1B0R3; -.
DR STRING; 45357.A0A2V1B0R3; -.
DR EnsemblFungi; CXQ85_003904-t46_1; CXQ85_003904-t46_1-p1; CXQ85_003904.
DR VEuPathDB; FungiDB:CXQ85_003904; -.
DR OrthoDB; 169924at2759; -.
DR Proteomes; UP000244309; Unassembled WGS sequence.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR10233; TRANSLATION INITIATION FACTOR EIF-2B; 1.
DR PANTHER; PTHR10233:SF14; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA; 1.
DR Pfam; PF01008; IF-2B; 2.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000244309}.
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 302..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 519 AA; 57813 MW; 74DAB3B6D4131E4B CRC64;
MSEPAAETPA QPKAPAQAKP AAEPENKALS NKELKELKKK EKAAKRAAQK EAAGISPEQQ
EQMAQQKMEK KKSSATNTNL KKQLSQAVVK DQSMKIPALF SHLETREQRN ASSPTVSHIV
HPSILTLSLH FANHKIVGST ARLRSMLEVF KTVIQDYKTP ENTTLTRHLT GHLSHQIEYL
KSSRPLSMSM GNAIRWLKQE ISLISIDTPE KEAKEILSGR IDDFIREKLE LSDQLIVENA
SQHISNGSTV LTFGHSEVLL KLFQYCALEQ EKSFNLVIVD SRPLFEGKKL LTELVNTKIP
NDSSRTDLDA DSETSSVIAR RSAPQTPITK DRIKVNYVLI NSLSSTIFED VDCVFLGAHA
MLSNGHLYSR VGTAMVAMMA HRRNIPVLTC CESIKFSDRV QLDSVTTNEL ADPEDLVKDS
SRKQPPQQGS LALEQFLKEV EQIEHEKKSK AGKKDKEPPK DISLENKSPL ADWKSIPSLN
LLNIMYDLTP PSYINKVVTE LGSLPPSSVP VILREYKSG
//
