ID A0A2V1BK95_9HELO Unreviewed; 901 AA.
AC A0A2V1BK95;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=EXS-domain-containing protein {ECO:0000313|EMBL:PVH73788.1};
GN ORFNames=DL98DRAFT_430666 {ECO:0000313|EMBL:PVH73788.1};
OS Cadophora sp. DSE1049.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiales incertae sedis; Cadophora.
OX NCBI_TaxID=1485229 {ECO:0000313|EMBL:PVH73788.1, ECO:0000313|Proteomes:UP000244409};
RN [1] {ECO:0000313|EMBL:PVH73788.1, ECO:0000313|Proteomes:UP000244409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE1049 {ECO:0000313|EMBL:PVH73788.1,
RC ECO:0000313|Proteomes:UP000244409};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; KZ804233; PVH73788.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1BK95; -.
DR STRING; 1485229.A0A2V1BK95; -.
DR Proteomes; UP000244409; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 2.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244409};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 691..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..388
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 579..773
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 35..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 769..796
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..818
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..879
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 901 AA; 103490 MW; 749AFAC41168D4DB CRC64;
MKFAKELEQD LVPEWRVKYL DYKAGKKHVK AVARAQTRMN ATPKTPAQPN LGPRNHSLYG
ATSPVAARNR PSATIARFDG TNDGPTESLR ASPAPLAADS RPQSDSSDEG PYAPLKKTPP
MPIPAHHDGP ADDGNYGSFV PTPPAKARPN FELPDPALEP TPLDVDMIAV DQVKKRQKDF
FKFMDKELEK VETFYKSKED EAGARLKILR EQLHEMRNRR IEEVAAAQNA KEVRRREENR
IFDFQGGRSN GQLKDDDYRP TSRDKLNTWL DPFEKAFGNA KAKVTGPRPG GNSKALQNMA
DSPELRSKAQ FDQNRQADEG RDYVRRPHYH DDVPYRTAKS KLKLALQEFY RGMELLKSYA
LLNRTAFRKI NKKYDKAVDA HPPLRYMSEK VNKAWFVNSD VLDSHLHAVE DLYARYFEKG
NHKVATGKLR SSTGRRKDQS ASAFRNGVLI GVGALFSIQG TIYGSDLLHD SDPVIRLQTS
YLLQIYGGYF LALYLFSWFC LDCSIWTHNK INYQFVFEFD PRHHLDWQQL SEFPSFLILI
WGLFVWLNFS RFGAPEMYIY YPVILIFVTV VLIFFPGPYI YHRSRRWFVY SHWRLLLAGL
YPCLRRYYDT RNVFPHLVNC GKYGMTILYY VALSIYRIDH GKGHLPVFIT FATINAIYCS
IWDLLMDWSL LQPHATKKYL RDVRGYKNPN YYYAAMILDP IFRFNWIFYA IYTHNLQHST
FVSFLVAFSE VTRRGVWVLF RVENEHCSNV ARNKASRDVP LPYSIASDSE EDSAPQEPIS
AETPPSQGSP TLSRHRSRIG TALEEQESGT SSMRRRPMTR TFTRIVADAH TQDFEKKRKP
GAGDSDNVNN RKRDGEDEDG EEQAGSSDDD DDDDDTQDVL DAEALLRERR RKESQIGEGS
G
//
