ID   A0A2V1CAR2_9HELO        Unreviewed;      1297 AA.
AC   A0A2V1CAR2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DL98DRAFT_620963 {ECO:0000313|EMBL:PVH82183.1};
OS   Cadophora sp. DSE1049.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiales incertae sedis; Cadophora.
OX   NCBI_TaxID=1485229 {ECO:0000313|EMBL:PVH82183.1, ECO:0000313|Proteomes:UP000244409};
RN   [1] {ECO:0000313|EMBL:PVH82183.1, ECO:0000313|Proteomes:UP000244409}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSE1049 {ECO:0000313|EMBL:PVH82183.1,
RC   ECO:0000313|Proteomes:UP000244409};
RX   PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA   Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA   Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA   Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT   "Comparative genomics provides insights into the lifestyle and reveals
RT   functional heterogeneity of dark septate endophytic fungi.";
RL   Sci. Rep. 8:6321-6321(2018).
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   EMBL; KZ804134; PVH82183.1; -; Genomic_DNA.
DR   STRING; 1485229.A0A2V1CAR2; -.
DR   Proteomes; UP000244409; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244409}.
FT   DOMAIN          11..224
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          244..538
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          664..720
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          740..1260
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1297 AA;  139920 MW;  25D799FF61D2A1ED CRC64;
     MPSIIEQCGL RISIDRGGTF TDCVARVPGK EDIVIKILSV DPRNYADAPS EAIRQVLELY
     HGTPIPRGSK LDLNGIEWIR MGTTVATNAL LERKGERTAL LITEGFKDLL HIGNQSRPHM
     FDMAISKPEV LYSKVVEVSE RVILEQCTES GRLKQPLNSP TPVSRSIGIT GEVVHIVKKL
     DVDQVRRDLQ DLVQEGYKAL AVCLMHSYTF TDHEIQILDL AKEAGFEHVS LSSQVSQRTK
     IVPRGNSATV DAYLTPAIQR YLDTFTSNFE DLEGSRTKIE FMQSDGGLVP HTKLSGLKSI
     LSGPAGGVVG YAETSYDLKN PVPVIGFDMG GTSTDVSRYN GSLEHIFETT TAGVVVQSPQ
     LDINTIAAGG GSILTWKNGL LTVGPESASS HPGPACYRKG GPLTVTDANL FLGRLVPKYF
     PSIFGPNENE PLDGDASSKK FQDITELINN ETGKSLSAEE IAEGFLKVAN ASMCGPIRTL
     TEGRGHDTSK HNLSCFGGAG GQHACSIAEN LRIKRVLVHK YSSILSAYGI GLADVVHEEQ
     LPCAKTFDSS TFSLITTDLD ALEDKARQCL LDNGFRGVTD CQRYLSMRYD GSDTSIMTPA
     DSENDIRKSF IDSHHREFGF TPKDRPIIVD ELRIRAVGES SASEEKSAFD ELRSLTTYVV
     PPKASLLQPV YFDQLGWTTT PVFTLQTLEA GTKVTGPALI IDKTQTILIN PKSVATILSS
     MVVIDVVAQS QASISSTTLD PIQLSVFRHR FMGVAEQMGR ALQKTSVSAN IKERLDFSCA
     IFTPEGDLVA NAPHVPAMIG SMAFAVRGQI ELWKGKLQDG DVLLSNSPER GGVHLPDFTV
     VTPVFDDQGI DIIFWAASRG HHADVGGILP GSMPPTSREI WEEGALVESF LLVRNGVFAE
     KELTKLIYED PAQYPGCSGT RCLGDNISDL KAQAAANYTG IRLIHQLIAE YTMDVVQYYM
     KAIQDSAELA VRNLLKDIAK ATGNVLQAVD FMDDGTPICL KITIDPGSGS AIFDFTGTGP
     EVYGNWNAPI AICNSAVIYS LRCLVKSDIP LNQGCINPIK IVVTEGSLLN PSPEAAVCAG
     NVLTSQRLVD VIFKAFGAMA ASQGCMNNFT FGINGEEGFG YYETICGGSG AGNGWHGTSG
     VHTNMTNTRI TDPESLERRY PVVLRKFSLR PGSGGDGQYR GGDGVVRDVE FRIPMTASIL
     SERRSFAPYG MNGGDDAARG LNQWVRKNGR TINLGGKNSV AVVAGERVVI NTPGGGGYGP
     KSERKDAGES VPNVKKSTFT AIANGTVEAI RSLGESA
//