ID A0A2V1D7E7_9PLEO Unreviewed; 350 AA.
AC A0A2V1D7E7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Di-copper centre-containing protein {ECO:0000313|EMBL:PVH94047.1};
GN ORFNames=DM02DRAFT_618883 {ECO:0000313|EMBL:PVH94047.1};
OS Periconia macrospinosa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX NCBI_TaxID=97972 {ECO:0000313|EMBL:PVH94047.1, ECO:0000313|Proteomes:UP000244855};
RN [1] {ECO:0000313|EMBL:PVH94047.1, ECO:0000313|Proteomes:UP000244855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE2036 {ECO:0000313|EMBL:PVH94047.1,
RC ECO:0000313|Proteomes:UP000244855};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; KZ805553; PVH94047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1D7E7; -.
DR STRING; 97972.A0A2V1D7E7; -.
DR Proteomes; UP000244855; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000244855};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..350
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016043194"
FT DOMAIN 85..102
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 231..242
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
FT REGION 262..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 38217 MW; 9B6ED5C4538DE99C CRC64;
MSSFKLVHAL LVAASVRLAV AQNNSSCTEI RARVSWTNLT SDEKTAYINA DLCLINAPAK
LGVEGAVTRW DDIQWPHVVQ AASVHGVGAF LPFHRYYLTA HEHLMRTECG YTGRMPYWDE
FAAIGRMYDT DMFDDQYFGG NGTDDGTYQV IDGQFANLTL RWLGDGSVKD HYLTRINDEG
ALNQTDQENI DKCNAITNYT SAWECWSGGP HSAGHQAISG IMGDGTLSPG DPLFYLHHSY
LDKLWWEWQK LDLPNRLLDM GGPNIPEAGS QPGGPSGGSN GTGVASARGV PENPSGHLGG
TGPEFTDYFG DNGGNVTTLN HTIYMANILP NVTIAQLMDL NGPVICSEYY
//
