ID A0A2V1DAQ3_9PLEO Unreviewed; 696 AA.
AC A0A2V1DAQ3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Acetyl-CoA synthetase-like protein {ECO:0000313|EMBL:PVH94244.1};
GN ORFNames=DM02DRAFT_676323 {ECO:0000313|EMBL:PVH94244.1};
OS Periconia macrospinosa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX NCBI_TaxID=97972 {ECO:0000313|EMBL:PVH94244.1, ECO:0000313|Proteomes:UP000244855};
RN [1] {ECO:0000313|EMBL:PVH94244.1, ECO:0000313|Proteomes:UP000244855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE2036 {ECO:0000313|EMBL:PVH94244.1,
RC ECO:0000313|Proteomes:UP000244855};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; KZ805544; PVH94244.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1DAQ3; -.
DR STRING; 97972.A0A2V1DAQ3; -.
DR Proteomes; UP000244855; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244855};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 121..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..66
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 73..484
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 551..634
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 696 AA; 76501 MW; B4C0FE1B35D28414 CRC64;
MSQDRVYAAS TADPVGFWGR QAANIYWHKQ PSDVIYKSKK TLIKSRISHS DWVWFPGGEI
STTYNAVDRH VLSGNGDNIA IIWDSPVTGA KEKYSYRQLL TEVETLAGVL REEGVRKGHV
VLIYMPMIPA ALFAMLAIAR IGAIHAVVFG GFSSPALAQR MEACRPHTVM TASCGIEGNK
GPTAYKRLIE EAIAKSKFKP NKTIVWQREQ LRWDPVLKED GQRNWQRLVK SARNRGLKAD
AVPIQSSDGL YIIYTSGTTG LPKGVLRTAG GHAVGLNFSI KYLFGVKGPG DVMFTASDIG
WVVGHSYILY APLLAGATTV LFEGKPVGTP DASTFWRMIN DYKVTSMFTA PTALRAIRRE
DPDNNHFREA YGKKGGLRSL RALFLAGERS EPSIVQMYQK LLHEYCADGA IVVDNWWSSE
SGSPISGIAL GASSGEDFPS TYKEKPLSIK PGSAGKALPG FDVQVVDDEG NEVKRGEMGN
LVLAVPLAPT AFTTLWEDEE RFYKGYLKRF NGQWLDTGDA GMMDDEGYIS VMSRADDVIN
VAAHRFSTGA IEQAITTHAG IAEAAVIGIP DQLKGHLPFA FITLSRHKHP EGAVPEEELF
KEVQMLIREQ IGAIAGLGGM IQGKGMIPKT RSGKTLRRVL RELMENATQG EMEREVAVPS
TIEDREAVSV ARAKVKEYFQ KKGKHLHRAT EARAKL
//
