ID   A0A2V1DG42_9PLEO        Unreviewed;       770 AA.
AC   A0A2V1DG42;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   22-FEB-2023, entry version 9.
DE   SubName: Full=Cullin-domain-containing protein {ECO:0000313|EMBL:PVH97126.1};
GN   ORFNames=DM02DRAFT_91726 {ECO:0000313|EMBL:PVH97126.1};
OS   Periconia macrospinosa.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX   NCBI_TaxID=97972 {ECO:0000313|EMBL:PVH97126.1, ECO:0000313|Proteomes:UP000244855};
RN   [1] {ECO:0000313|EMBL:PVH97126.1, ECO:0000313|Proteomes:UP000244855}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSE2036 {ECO:0000313|EMBL:PVH97126.1,
RC   ECO:0000313|Proteomes:UP000244855};
RX   PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA   Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA   Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA   Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT   "Comparative genomics provides insights into the lifestyle and reveals
RT   functional heterogeneity of dark septate endophytic fungi.";
RL   Sci. Rep. 8:6321-6321(2018).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KZ805445; PVH97126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2V1DG42; -.
DR   STRING; 97972.A0A2V1DG42; -.
DR   Proteomes; UP000244855; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244855};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          406..645
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   770 AA;  88935 MW;  174035256CF6B789 CRC64;
     MASSNMPPVP AKNDVKATWA YLEAGVEKIM TNLRGGMDMK TYMGLYTAIH NFCTAEKAVA
     GTSFTSHTNR GGAHLLGEDL YQHLIEYLKA HLKDVQARSK EHTDEALLTF YIKEWNRYTT
     AGQYNNHLFR YLNRHWVKRE MDEGKKHIYD IYTLHLVRWK EDMFIGTQES VMRSVLKLVE
     KQRNGETIEQ SYIKSVVDSF VSLGLDEQDS SKSTLDVYRE YFEKPFLEAT AEYYNNESKQ
     FLAENSVVEY MKKAEARLDE EKDRVPLYLL NEIMTPLMRT CEQALITNHS EALRDEFQNL
     LNHDKQEDLG RMYKLLARIP EGLDPLRTKF ETHVRKAGIE AVNKISAEGD KIEPKVYVDA
     LLEVHTQYQE LVNRAFNGES EFVRSLDNAC REFVNRNKIC KSGSNKSPEL LAKYTDTLLK
     KSSAKMNEED NIENLLSQVM TVFKYIEDKD VFQKFYSRML AKRLVQATSA SDDSETTMIS
     KLKEACGFEY TNKLQRMFQD MQISKDLNSA YKDWLGKTLD DGDLKNSVDA TYHILGTGFW
     PLNNPTTSFT PPQLIVQTYE RFSRFYNNKH QGRKLTWLWH LSKGEMKANY CKVAGQKASP
     TLQVSTFQMA ILLLFNDSET VAYDEIAEAT KLDKDTLDPS IGVFIKAKVL IAEPEGAKPE
     SGTTYKLNYG FKPKKIKINL NIAIKGEQKQ ETEDTHKTIE EDRKLLMQSA IVRIMKSRKK
     MKHQQLVSET IQQIKSRFMP RVPDIKKCID ILLEKEYLER LDGDELGYLA
//