ID A0A2V1E070_9PLEO Unreviewed; 1209 AA.
AC A0A2V1E070;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Myosin-1 {ECO:0000256|ARBA:ARBA00016187};
DE AltName: Full=Class I unconventional myosin {ECO:0000256|ARBA:ARBA00032645};
DE AltName: Full=Type I myosin {ECO:0000256|ARBA:ARBA00029665};
GN ORFNames=DM02DRAFT_587214 {ECO:0000313|EMBL:PVI03676.1};
OS Periconia macrospinosa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX NCBI_TaxID=97972 {ECO:0000313|EMBL:PVI03676.1, ECO:0000313|Proteomes:UP000244855};
RN [1] {ECO:0000313|EMBL:PVI03676.1, ECO:0000313|Proteomes:UP000244855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE2036 {ECO:0000313|EMBL:PVI03676.1,
RC ECO:0000313|Proteomes:UP000244855};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC {ECO:0000256|ARBA:ARBA00004134}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KZ805328; PVI03676.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1E070; -.
DR STRING; 97972.A0A2V1E070; -.
DR Proteomes; UP000244855; Unassembled WGS sequence.
DR GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR CDD; cd01378; MYSc_Myo1; 1.
DR CDD; cd11858; SH3_Myosin-I_fungi; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035535; Fungal_myosin-I_SH3.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF837; MYOSIN-3-RELATED; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000244855};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 37..716
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 774..963
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT DOMAIN 1058..1119
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..611
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 929..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1040
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1059
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 130..137
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1209 AA; 133278 MW; C06CD5322D82ACED CRC64;
MKAVSKRAGR KKEGGGGAPK QQFAKKAVFE STKKKEVGVS DLTLISKISN EAINENLKKR
FENAEIYTYI GHVLVSVNPF RDLGIYTDQV LESYKGKNRL EMPPHVFAIA ESAYYNMNAY
KDNQCVIISG ESGAGKTEAA KRIMQYIANV SGGSNTSIQE IKDMVLATNP LLESFGNAKT
LRNNNSSRFG KYLEIQFNAQ GEPVGANINN YLLEKSRVVG QITNERNFHI FYQFAKAASE
SHRQTFGIQQ PQSYVYTSRS KCYDVPGIDD HAEFKDTLNA MKVIGLSQAE QDNIFRMLAA
ILWLGNVSFQ EDDSGNAAIV DQSVVDFVAY LLEVESAHVN KALSTRVMET SRGGRRGSVY
DVPLNPAQAM AVRDALAKGI YFNLFDWIVQ RVNVSLQARG AMSHSIGILD IYGFEIFEKN
SFEQLCINYV NEKLQQIFIQ LTLKAEQEEY AREQIKWTPI KYFDNKVVCE LIEEKRPPGV
FSFLNDACAI ANADPAAADQ TFAQRLGALS TNPNFEPRQG RFVIKHYAGD VAYAVDGMTD
KNKDQLLKDL LLLLGNSSNS FVHTLFPDQV NTDDRRRPPT AGDKIKASAN DLVSTLMKAQ
PSYIRTIKPN ENKSPSEFNE PNVLHQIKYL GLQENVRIRR AGFASRQTFE KFVERFFLLS
PKTGYAGEYT WSGDYQSGAK QILRDTNIPA EEFQMGTTKV FIKTPETLFA LETMRDRYWH
NMAIRIQRAW RNYLRYRAEC ATRIQRFWRR VNGGMEFIQV RDEGHKILGG QKERRRFSLI
GSRRFMGDYL GIGNKGGPGE VIANAIGISG EEVVFSSRAE VLVSKLGRSS KPEARQLALT
KKNVYLIKQV LANRQIQIQA ERTIPVGAIK YISCSKLKDD WFSIGVGSPQ EPDPLVSCVF
KTEFFTHLKH VLRGSLNLKI GDTIEYNKKP GKPAQIKTMK DPAVPRDDTY KSGTIHTGPG
EPPNSVSKPT PKGKQVAAKP ITKGKLLRPG GPGGGPSKLA SRPAQSRPTP AAVPQPKPVP
QPVAALSNGS SHARSSSASS NRAPPPPPPA PPAAPPAPKE PTYRAMYDFA GQSAGELSIK
KDEIILVTQK EGNGWWLAQR LDKSASGWAP SAYLEEFVSK PAPPPAPPRP AAGSNGVRGK
PAPPAPPAKR PAAKNRPPVG GAARDSGYSG SNSDAGARDS GGSIAGGLAE ALRQRQAAMQ
GKKADDDDW
//
