ID A0A2V1E1B3_9PLEO Unreviewed; 404 AA.
AC A0A2V1E1B3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Delta(12) fatty acid desaturase {ECO:0000313|EMBL:PVI04211.1};
GN ORFNames=DM02DRAFT_556650 {ECO:0000313|EMBL:PVI04211.1};
OS Periconia macrospinosa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX NCBI_TaxID=97972 {ECO:0000313|EMBL:PVI04211.1, ECO:0000313|Proteomes:UP000244855};
RN [1] {ECO:0000313|EMBL:PVI04211.1, ECO:0000313|Proteomes:UP000244855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE2036 {ECO:0000313|EMBL:PVI04211.1,
RC ECO:0000313|Proteomes:UP000244855};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
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DR EMBL; KZ805323; PVI04211.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1E1B3; -.
DR STRING; 97972.A0A2V1E1B3; -.
DR Proteomes; UP000244855; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF19; BIFUNCTIONAL OELATE_LINOLEIC ACID DELTA DESATURASE (EUROFUNG); 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244855};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..64
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 84..367
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 404 AA; 45402 MW; 8C9C52667F6B7386 CRC64;
MIITTSRVQA PTVKTRLTAV ADVKPTPIPD IKTLKDAIPA HCFERSMIRS FSYVVRDLII
VSGLFYSAVW LSQLNAPTYI LVPLWALYSF VQGCFFTGLW ILAHDCGHDS FSANLTVNAV
TGWFLHSMLM VPFFSWKFSH ARHHRYHNHM EKDTVFVPSR KSEAKTSPTL WQKITDHAAA
DTPIVTVAAL LFHQLLGWPA YILMNAGAGP KSLTKSDRKK SSAYKQSHLD PTAHVFTPSE
APFVALSNVG LLITMSALYL ASRSVGGWTV SLAYGLPYLW MNHWIVAITY LHHTHPEAPH
YEADEWTFVK GAASTVDREF GFIGRHIFHG IIEYHVVHHM FPRIPFYHAE EATGAIAPLL
GERYIEQKST SFLNDLWQSF TNLKYVEPGK GAHAGGLVWS QIKA
//
