ID A0A2V1EB74_9PLEO Unreviewed; 241 AA.
AC A0A2V1EB74;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DNA replication complex GINS protein PSF2 {ECO:0000256|ARBA:ARBA00015139, ECO:0000256|PIRNR:PIRNR028998};
GN ORFNames=DM02DRAFT_696434 {ECO:0000313|EMBL:PVI07787.1};
OS Periconia macrospinosa.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX NCBI_TaxID=97972 {ECO:0000313|EMBL:PVI07787.1, ECO:0000313|Proteomes:UP000244855};
RN [1] {ECO:0000313|EMBL:PVI07787.1, ECO:0000313|Proteomes:UP000244855}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSE2036 {ECO:0000313|EMBL:PVI07787.1,
RC ECO:0000313|Proteomes:UP000244855};
RX PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT "Comparative genomics provides insights into the lifestyle and reveals
RT functional heterogeneity of dark septate endophytic fungi.";
RL Sci. Rep. 8:6321-6321(2018).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation.
CC {ECO:0000256|ARBA:ARBA00025163}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR028998}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family.
CC {ECO:0000256|ARBA:ARBA00010565, ECO:0000256|PIRNR:PIRNR028998}.
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DR EMBL; KZ805302; PVI07787.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V1EB74; -.
DR STRING; 97972.A0A2V1EB74; -.
DR Proteomes; UP000244855; Unassembled WGS sequence.
DR GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR GO; GO:0032993; C:protein-DNA complex; IEA:UniProt.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:UniProt.
DR CDD; cd11712; GINS_A_psf2; 1.
DR CDD; cd21694; GINS_B_Psf2; 1.
DR Gene3D; 1.20.58.1020; -; 1.
DR Gene3D; 3.40.5.50; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR PANTHER; PTHR12772:SF0; DNA REPLICATION COMPLEX GINS PROTEIN PSF2; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
DR SUPFAM; SSF160059; PriA/YqbF domain; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR028998};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR028998};
KW Reference proteome {ECO:0000313|Proteomes:UP000244855}.
FT DOMAIN 51..189
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
FT REGION 208..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 241 AA; 26514 MW; 16BE6CC50E8EB26F CRC64;
MALPLPPGLT PPEIAFICEM ELVTIIPRQK LEGLKLLGGP LKPLNPPQRA SIPLWLALLL
KRQRRANIVP PPWLSPIPLK AILDLETEQG DTFSPPPRLP PASSNNAVPF SPPFLQSSTA
NAAPDALPYH WLELGEMLLE AAADDFEEPD NVRKLLRGLR EVRMAKLRQG VEVLDAGGGV
KMNGVGAMEL GEARSFITGV IDGLRKISAS REQQRKDRAR EERENGYSGS ADYDDDEMDM
Q
//
