ID   A0A2V1ECJ3_9PLEO        Unreviewed;      2058 AA.
AC   A0A2V1ECJ3;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Negative regulator of mitosis {ECO:0000313|EMBL:PVI06975.1};
GN   ORFNames=DM02DRAFT_667113 {ECO:0000313|EMBL:PVI06975.1};
OS   Periconia macrospinosa.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Massarineae; Periconiaceae; Periconia.
OX   NCBI_TaxID=97972 {ECO:0000313|EMBL:PVI06975.1, ECO:0000313|Proteomes:UP000244855};
RN   [1] {ECO:0000313|EMBL:PVI06975.1, ECO:0000313|Proteomes:UP000244855}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSE2036 {ECO:0000313|EMBL:PVI06975.1,
RC   ECO:0000313|Proteomes:UP000244855};
RX   PubMed=29679020; DOI=10.1038/s41598-018-24686-4;
RA   Knapp D.G., Nemeth J.B., Barry K., Hainaut M., Henrissat B., Johnson J.,
RA   Kuo A., Lim J.H.P., Lipzen A., Nolan M., Ohm R.A., Tamas L.,
RA   Grigoriev I.V., Spatafora J.W., Nagy L.G., Kovacs G.M.;
RT   "Comparative genomics provides insights into the lifestyle and reveals
RT   functional heterogeneity of dark septate endophytic fungi.";
RL   Sci. Rep. 8:6321-6321(2018).
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
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DR   EMBL; KZ805306; PVI06975.1; -; Genomic_DNA.
DR   STRING; 97972.A0A2V1ECJ3; -.
DR   Proteomes; UP000244855; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244855}.
FT   DOMAIN          30..845
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   REGION          356..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          503..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          857..884
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1202..1227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1851..1875
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..453
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1202..1225
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1851..1870
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2058 AA;  229189 MW;  2A60A003C42D98DC CRC64;
     MAALHSTGVR KPAALPYLIA ESILDQNCTE HDYTWETYRD EDPNSPTEEV VTTTHHVVWS
     RGGVVRKVFN FEIEKEPVIQ ALLTWFPTEQ QTTASAKVAK DGLELDLQRT FLTQGTQPAT
     DPNAPHEQVF TTKEVKSRAL VVFLRSQAHV FFLSGTTHVV NLPFEVDKAF PAARGLILQR
     KIVTPKAIPS SPQLPSAPPN SFLTNPQSFL SQTFTQSFTH PHRHTSSLGP SRLSMGLKPG
     PAMPLFLEEL AKSSAVANTE GLPRLYSFTD PLAELGLVVN VTTSHERDSL LTINGAGHRR
     LEAIDKAEEV IYVSAKNEIL FDQSGNDKPL LLVITSNYKT NKFTIWSAAY MEPKPISNSR
     KQHAPLSVHK SRRRSSYGPT APGTGATTPA VRGPDRLRES LGGTIKNKPQ PPSFKATSQN
     RERLSDQAVE DALSSQLNPT FDPARQPNES RRVSSLLSRA ELSTSFDKTA FQDLATQRHS
     LGGSFNASFG ASQRSRHSLG TERLSFGGFN QSRHRASTPG SMTSRMSLGG ASVDDTFDEM
     MDDTFDTIED YDELDDLFAP VDSGADHDSM ESLRKELIMS VVAEIPAQNF LKAGRFALND
     PTAESQSSSK VFTLTAPFNS ATLHERKLFL YIVHSSLEHP LECELSITRK RLSPSASTTQ
     SIMQTAAPRY ACAPKFVQIQ ELKDARDAVK IKDGHTERVA CLISANPSEP CISISAAWGT
     HLPTNFALGT ARLFNPYAVL QDEQSRVDAG LKRTVNVQNP LLQVLCPGPT GTFEVVDGKS
     HRHSHQIRLL PKSDRVAALF RVLSLILPDY AGDFLLEIWW NMRKLLPTEQ QQGLKGDWTA
     FVATLFTMAV PFVDERSKKT GRKSKVSQGR GMERSQHDAD EDAENPAWRI MCSRQLSHSH
     AKIWENNAWQ WVQQARPAAD MMSPLSKRTQ KHQSPCIGQQ IAGKQSMLIS CAELARQFNQ
     SPIGKAASDH WRRLSPSEKQ DLRISTLSEI VVILHLYRED LKLDVLANDY TRAEAGNLAP
     VLAQIGHWLR WDGWGRRQGA YYDLDGGSSE QWIYEDTSFL PSVRLHPQPW DNPPSILEWL
     STVSGVHTYT PFPTLATLIR KSKASPHSSV NIDEIVSAVT PRTVALQWYF RDVDYTLNPR
     KAVELIEKVG ITTQILATLP EAAQAPLMEF ITRCQANPPA TWSSSLLRLV QREDLDLTLT
     SGHDATQDTH QSHGHVSTNY QPSLHAPGPT RDIHTICQSA ERTETLASTA ESDRHTITRL
     IFREDRRFME AYILVEPTKP SLAYYEHDSR AEDAAILEGQ KVLVQWVMIR TFSLPIGSSM
     LKFSSKKPLL TEKFNLIGFS TSCVMKPMGN VVTADRTTYS EEKFFWAFFN QGVSAGLSIS
     RDAQGIDTSW IMYNKPADLS NRHAGLLLGL GLNGHLKNIA KWLSFKYLTP KHTMTSVGLL
     LGLSASYMGT MDTLVTRLLS VHVTRMLPPG AAELNLSPYT QTTGLMGIGL LYYNTQHRRM
     SEVMISEIEH VDAPDPSEPP DTLRDEAYRL AAGFALGFIN LGKGKDLRGL HDMRIVERLL
     GIAMGPKSVD IIHILDQATA GAVIAIALIF MKTHDEAVAR KIDIPDTLPQ FDYVRPDICL
     IRTLAKHMIM WDNIVANDEW ITKNLPLEYR SNHDLRGITK LRSEQMPFFN VLSGLLWSIS
     LKYAGTGNTQ VRDFLIRYLD QLIRINKLPA HRYDAKLARN TVRNCQDLVA LSAATVMAGT
     GDIDIFRRLR GLHGRIGQDV PYGSHLAAHM AIGVLFIGGG TYTFNTSNKA IASLICAFYP
     LFPLDVQDSR AHLQAFRHFW VLAAEPRALI VRDADTGKAF STPITVYMRD NADTNSSSSP
     TPSTTSGDEP KRHMTAPCLL PDLSTISRIE TSDPTYWPTT LDFVVNPLHL QRFRHTQTLT
     VRRRSPHDQH GTTFSATLVA LNDAQSSRSA RLMWDWLFTL PALTQFEKAN VGLVLPTDPY
     SSTFLDDGAT VVDHRLVLAR LSRSWKARDL WVLRGVFEWA GSVVARGDGR VRWLGREVLE
     RLRAGVLERG RVVGKDGG
//