ID A0A2V2NFU6_9EURY Unreviewed; 563 AA.
AC A0A2V2NFU6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DK846_03255 {ECO:0000313|EMBL:PWR74183.1};
OS Methanospirillum lacunae.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX NCBI_TaxID=668570 {ECO:0000313|EMBL:PWR74183.1, ECO:0000313|Proteomes:UP000245657};
RN [1] {ECO:0000313|EMBL:PWR74183.1, ECO:0000313|Proteomes:UP000245657}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ki8-1 {ECO:0000313|EMBL:PWR74183.1,
RC ECO:0000313|Proteomes:UP000245657};
RA Dueholm M.S., Nielsen P.H., Bakmann L.F., Otzen D.E.;
RT "Draft genome of Methanospirillum lacunae Ki8-1.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWR74183.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QGMY01000002; PWR74183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V2NFU6; -.
DR OrthoDB; 8127at2157; -.
DR Proteomes; UP000245657; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245657};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..272
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 455..553
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 563 AA; 63437 MW; C261D44B31570138 CRC64;
MVFDIKTLIL INFLVNFVNV FVAFIIWQQY KRRFSGLTCL LASMIMEAGG IGLVLFNGTI
PDFFSIVLGN GMMLIGWVFL LIGLERFTGK PGPQIQNFIL LAIFFISETY FLYIQPNLSL
RENVMEFLIV LIDLQLCYLL FGKISGSIKK TTQIIAHVMG IHLVFSIILL VLEFLFPFKG
NKFFFSGMIG EIIPTTYLLM GILVIIAFIM MVTSRLLEEI RAQEEKFNTA FHSSPYAIII
TRVSDGGIFE INDGFTAITG YQPEEVLGKT TVELSIWEKP RDRSLLVTDI TKGKVRGVQV
EIRAKSGKII SGLFSADIVT INSEQCILSS VSDITELKHT EQALIQANRK LNLLSSITRH
DILNRTMVIQ FYGQELIENL PGDSYQKEIN AIVQSTAEIR TIIEFTGEYQ ELGSSAPEWQ
NLEKLFSSPE IQKFMSDISF QSDLGTLEIY ADLMLRKVVY NLVENSHRHG NKVTQISLSS
HTENKDLLIW YKDNGGGIPL DEKEKSFEKG YGKNTGLGLF LIREILSITG ISIHETGVPG
IGVKFEIRVP EGKYRNAHTN PSQ
//
