ID A0A2V2PZN7_9ACTN Unreviewed; 106 AA.
AC A0A2V2PZN7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=QacE family quaternary ammonium compound efflux SMR transporter {ECO:0000313|EMBL:PWS43036.1};
GN ORFNames=DKT74_18910 {ECO:0000313|EMBL:PWS43036.1};
OS Streptomyces sp. ZEA17I.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2202516 {ECO:0000313|EMBL:PWS43036.1, ECO:0000313|Proteomes:UP000245984};
RN [1] {ECO:0000313|EMBL:PWS43036.1, ECO:0000313|Proteomes:UP000245984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZEA17I {ECO:0000313|EMBL:PWS43036.1,
RC ECO:0000313|Proteomes:UP000245984};
RA Chen X., Qin K., Li H., Cortesi P., Saracchi M., Sang W., Yang M.;
RT "Genome sequencing and identification of chitinase family genes of
RT Streptomyces sp. ZEA17I, a biocontrol agent against plant pathogens.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC {ECO:0000256|RuleBase:RU003942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWS43036.1}.
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DR EMBL; QGMS01001182; PWS43036.1; -; Genomic_DNA.
DR RefSeq; WP_018488630.1; NZ_QGMS01001182.1.
DR AlphaFoldDB; A0A2V2PZN7; -.
DR Proteomes; UP000245984; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR InterPro; IPR045324; Small_multidrug_res.
DR PANTHER; PTHR30561:SF0; GUANIDINIUM EXPORTER; 1.
DR PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR Pfam; PF00893; Multi_Drug_Res; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 106 AA; 10997 MW; 1F00BA2C4866382A CRC64;
MAWVLLIIAG LLEVGWSIGM KYTEGFTRLW PSVFTGLGIV ASMVLLSHAA KTLPIGTAYG
VWVGIGAAGA AILGMVVLNE PVTAARIFFV CLLLVAVVGL KATSGH
//
