ID A0A2V2YYA4_9BACL Unreviewed; 600 AA.
AC A0A2V2YYA4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DFQ01_102130 {ECO:0000313|EMBL:PWW07238.1};
OS Paenibacillus cellulosilyticus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=375489 {ECO:0000313|EMBL:PWW07238.1, ECO:0000313|Proteomes:UP000246635};
RN [1] {ECO:0000313|EMBL:PWW07238.1, ECO:0000313|Proteomes:UP000246635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5696 {ECO:0000313|EMBL:PWW07238.1,
RC ECO:0000313|Proteomes:UP000246635};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWW07238.1}.
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DR EMBL; QGTQ01000002; PWW07238.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V2YYA4; -.
DR Proteomes; UP000246635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PWW07238.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000246635};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 299..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 320..372
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 486..589
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 600 AA; 68260 MW; C0D193732998F2D0 CRC64;
MDKPFKKGIS FRNKLLVTFL LVSLLPMLAV EMMSYYTSTV AMKTNMNDLI NVNLLQTSKN
LDTSMQDYED LLFQVFTDDN VMSLVKEIND PTAESPEFSR RKLINILSRY SYAKEGIRSI
AIFTSNNTLI TYDRQTGSPY DNMWSSVKDL IHLPIYQKAI DGKGQPVITP PLKIDTINNN
EQYGFHLARQ LSDLNVASLE PIGVAVITVY ESVLAQAINL EEPSTANDSP RLNKRNFLTD
KSGIIVSSPD KSQIGLNVND IVTDSTILNT YYNMSSKLWV NNLVDQNQLF KEMYAMQHLT
LYFGLSAAVL TVILITIFSG RLTRSIRRIL KAMRTAQHGT LDVQVEGTAH DDLSVIALSF
NKMMLKVSEL MNESKSAIEK QKEAEIRALE AQINPHFLYN TLDSINWMAI EKEEYQISQM
LKELAQILRY SVKDSNKRVT LREELKWMNS YVYLQQHRFR SSFNCEVECP EHLHHCPVHK
LTFQPFIENA IIHGFYGVNS GGLLRIVVKE LDTKQLMIRI EDNGVGMPED KRKTLLSEHQ
SEDEAAGSGL GVRNVADRIR SYYGNRGHLD IQSELGQGTV VTITLPMDTE GEEEDANRRR
//
