ID A0A2V3JKV2_9EURY Unreviewed; 497 AA.
AC A0A2V3JKV2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:PXF59850.1};
GN ORFNames=C4B59_10610 {ECO:0000313|EMBL:PXF59850.1};
OS ANME-2 cluster archaeon.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinales incertae sedis; ANME-2 cluster.
OX NCBI_TaxID=2056317 {ECO:0000313|EMBL:PXF59850.1, ECO:0000313|Proteomes:UP000248329};
RN [1] {ECO:0000313|EMBL:PXF59850.1, ECO:0000313|Proteomes:UP000248329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E20ANME2 {ECO:0000313|EMBL:PXF59850.1};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PXF59850.1}.
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DR EMBL; PQXF01000021; PXF59850.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2V3JKV2; -.
DR Proteomes; UP000248329; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR42682:SF3; HYDROGENASE-4 COMPONENT B; 1.
DR PANTHER; PTHR42682; HYDROGENASE-4 COMPONENT F; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000248329};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..426
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 497 AA; 54115 MW; 670D21898E7E893C CRC64;
MMVIEINSIT PLLAVLVSMV ASVMILAFGK YPNIREGWTF VAAFIKFGLV ISMLPLILKG
NVVTYTVVEM LPNLPIAFKV DAFGILFAIT SSFLWIFVTS YSIGYMRSLK EHAQTRYFFC
FAIALSSAVG IAFSANLVTL FLFYELLTIS TYPLVAHIET PEAISSGRKY LTYLMIAGVS
LLFSIVVVYH YTGTTEFSFA GIAGMETIPQ TTLVILFITF MIGCAKAAFM PLHAWLPAAM
IAPTPVSALL HAVAVVKAGV FTALRVILYV FGVDLMQGSG LWLYMAYFVS ITIILASIYA
LMQDNLKKRL AYSTVSQLSY IVLGAVLITP HGLTGGMLHI PYHAFMKITL FMCAGALIVT
AKKENISEMK GIARQMPITM IAFTVGALGM IGMPPVGGYV TKWFLLLGAA ELHSMILIAV
LLVSAILNAA YFFPVIYVAF FKKPDHELKY KEAPLTMLVP LVLTAIVSIV IGIWPDAPGM
FLDIVEIAVA NVTGGGI
//
