ID   A0A2V3PNQ3_9BACT        Unreviewed;       788 AA.
AC   A0A2V3PNQ3;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=CLV62_11163 {ECO:0000313|EMBL:PXV64105.1};
OS   Dysgonomonas alginatilytica.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae;
OC   Dysgonomonas.
OX   NCBI_TaxID=1605892 {ECO:0000313|EMBL:PXV64105.1, ECO:0000313|Proteomes:UP000247973};
RN   [1] {ECO:0000313|EMBL:PXV64105.1, ECO:0000313|Proteomes:UP000247973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100214 {ECO:0000313|EMBL:PXV64105.1,
RC   ECO:0000313|Proteomes:UP000247973};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PXV64105.1}.
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DR   EMBL; QICL01000011; PXV64105.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2V3PNQ3; -.
DR   Proteomes; UP000247973; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR026876; Fn3_assoc_repeat.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF13287; Fn3_assoc; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          40..169
FT                   /note="Beta-hexosaminidase bacterial type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02838"
FT   DOMAIN          172..521
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   DOMAIN          670..770
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|Pfam:PF00754"
FT   ACT_SITE        346
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   788 AA;  89664 MW;  D83B04842F812391 CRC64;
     MTHFPILKRI ITLRLFLITV FSISLLSACT NENQSAKADY SIIPLPQQVV LQSDKEPFIL
     DKSTKILYLE NDNESYQLAT FLAAYVKECV GIELQLTTKD EGENIIKFQI DDAIDKNPDY
     YNLSITNNHI IIQATSGAGI FYGIQTLRKS LPVENINNVS FPAVVIKDYP KFSHRGVSLD
     VSRHFYSADF IKKYIDVLAL FNMNVFHWHL TDDQGWRIEI KKYPNLTKIG SQRSETAIDR
     HSEEYDGKPY GGFYTQEEIK EVVEYARQRF ITVIPEIDVP GHTLAVLASY PELGCTGGPY
     QVGRDWGIYE DVLCAGNDSV FTFLDDVFTE VVALFPAKYI HIGGDECLKN RWMACPKCQE
     RIKSLGIKVK KAAPVGEQLQ SYFIHRVEEM INKKGRSIIG WDEILEGGIA PNATIMSWRG
     TDGGIYAANR DHDVIMTPES HLYLDYYQSP DVDNEPYTFG WLTDLEKVYS FDPIPAELEK
     DQQKHILGGQ VNVWAEYLPT SKNVEYMLLP RMAALSETLW SYPQEKDYNN FVARMYRQSL
     LLDKLGYENC KQAYGVQAKY DYNTEMSEIK ITLSTFDNAP IYYTLDGTAP TEKSLKYSEP
     IIISKSSELK SLVVRNGKQD NTYSKEFSFN KATARPIELK NQPDKKYTFN GAVTLVDGQR
     GYKNSYRTGS WLGFLGEDMV ATIKLGDQVP ISSVKLNQFV NSRGGLFFAK SIKIEMSDDG
     KTFREVSSKT QPILNEHIKP QIFEVKETFD TVKANYIRVT LEAIDGLPSW HEKAGAMAYI
     MVDEIVVE
//